Version 5.4
| Mus musculus Protein: Zscan4f | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-142955.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Zscan4f | ||||||||
| Protein Name | zinc finger and SCAN domain containing 4F | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000089014 | ||||||||
| InnateDB Gene | IDBG-142953 (Zscan4f) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Transcription factor required to regulate early development. Binds telomeres and plays a key role in genomic stability by regulating telomere elongation. Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Nucleus {ECO:0000255PROSITE- ProRule:PRU00187}. Chromosome, telomere {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Up-regulated in blastocyst outgrowths and is detectable in a mosaic fashion in ES cultures. {ECO:0000269PubMed:17553482}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:3708485 | ||||||||
| InterPro |
IPR003309
Transcription regulator SCAN IPR007087 Zinc finger, C2H2 IPR008916 Retrovirus capsid, C-terminal IPR015880 Zinc finger, C2H2-like |
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| PFAM |
PF02023
PF00096 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00431
SM00355 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q3URS2 | ||||||||
| PhosphoSite | PhosphoSite-Q3URS2 | ||||||||
| TrEMBL | L7N266 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 665902 | ||||||||
| UniGene | Mm.425380 | ||||||||
| RefSeq | XP_003688791 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Zscan4f | ||||||||
| OMIM | |||||||||
| CCDS | CCDS52015 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AC155315 AK141250 | ||||||||
| GenPept | BAE24616 | ||||||||