Mus musculus Protein: Card9
Summary
InnateDB Protein IDBP-148498.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Card9
Protein Name caspase recruitment domain family, member 9
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000097876
InnateDB Gene IDBG-148496 (Card9)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0050700 CARD domain binding
Biological Process
GO:0009620 response to fungus
GO:0032494 response to peptidoglycan
GO:0032495 response to muramyl dipeptide
GO:0032755 positive regulation of interleukin-6 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0032874 positive regulation of stress-activated MAPK cascade
GO:0042493 response to drug
GO:0042534 regulation of tumor necrosis factor biosynthetic process
GO:0042981 regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043330 response to exogenous dsRNA
GO:0045076 regulation of interleukin-2 biosynthetic process
GO:0045087 innate immune response (InnateDB)
GO:0045089 positive regulation of innate immune response
GO:0045408 regulation of interleukin-6 biosynthetic process
GO:0046330 positive regulation of JNK cascade
GO:0050830 defense response to Gram-positive bacterium
GO:0051607 defense response to virus
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005829 cytosol
Protein Structure and Domains
PDB ID MGI:2685628
InterPro IPR001315 CARD domain
IPR011029 Death-like domain
PFAM PF00619
PRINTS
PIRSF
SMART SM00114
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A2AIV8
PhosphoSite PhosphoSite-A2AIV8
TrEMBL Q6P065
UniProt Splice Variant
Entrez Gene 332579
UniGene Mm.330064
RefSeq NP_001032836
MGI ID
MGI Symbol Card9
OMIM
CCDS CCDS38084
HPRD
IMGT
EMBL AL732541 BC065797 BC151023
GenPept AAH65797 AAI51024