InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Il22

Summary

InnateDB Protein

IDBP-192085.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Il22

Protein Name

interleukin 22

Synonyms

IL-22; IL-22a; Iltif; ILTIFa;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000094449

InnateDB Gene

IDBG-192083 (Il22)

Protein Structure

UniProt Annotation

Function

Cytokine that contributes to the inflammatory response in vivo.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005125	cytokine activity
GO:0005515	protein binding

Biological Process

GO:0042516	regulation of tyrosine phosphorylation of Stat3 protein
GO:0045087	innate immune response (InnateDB)
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0050728	negative regulation of inflammatory response
GO:0072593	reactive oxygen species metabolic process