InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TET2

Summary

InnateDB Protein

IDBP-480846.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TET2

Protein Name

tet methylcytosine dioxygenase 2

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000425443

InnateDB Gene

IDBG-32690 (TET2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	8 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0008198	ferrous iron binding
GO:0008270	zinc ion binding
GO:0070579	methylcytosine dioxygenase activity

Biological Process

GO:0006211	5-methylcytosine catabolic process
GO:0006493	protein O-linked glycosylation
GO:0007049	cell cycle
GO:0030099	myeloid cell differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0055114	oxidation-reduction process
GO:0080111	DNA demethylation
GO:0080182	histone H3-K4 trimethylation