Version 5.4
Homo sapiens Protein: ITGB1
Summary
InnateDB Protein IDBP-592515.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ITGB1
Protein Name integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
Synonyms CD29; FNRB; GPIIA; MDF2; MSK12; VLA-BETA; VLAB;
Species Homo sapiens
Ensembl Protein ENSP00000431326
InnateDB Gene IDBG-68302 (ITGB1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 128 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Experimentally validated
Total 128 [view]
Protein-Protein 127 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
Biological Process
GO:0007275 multicellular organismal development
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR002369 Integrin beta subunit, N-terminal
IPR015812 Integrin beta subunit
IPR016201 Plexin-like fold
PFAM PF00362
PRINTS PR01186
PIRSF PIRSF002512
SMART SM00187
SM00423
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5T3E6
UniProt Splice Variant
Entrez Gene 3688
UniGene Hs.643813
RefSeq
HUGO HGNC:6153
OMIM 135630
CCDS
HPRD 00628
IMGT
EMBL AL365203
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca