InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fcrl5

Summary

InnateDB Protein

IDBP-620082.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fcrl5

Protein Name

Fc receptor-like 5

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000131176

InnateDB Gene

IDBG-157234 (Fcrl5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Preferentially expressed in marginal zone B cells. {ECO:0000269PubMed:15302849}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0045087	innate immune response (InnateDB)
GO:0050859	negative regulation of B cell receptor signaling pathway
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0043235	receptor complex

Protein Structure and Domains

PDB ID

MGI:3053558

InterPro

IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013151 Immunoglobulin

PFAM

PF07679
PF00047

PRINTS

PIRSF

SMART

SM00408
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q68SN8