Version 5.4
Mus musculus Protein: Skint8
Summary
InnateDB Protein IDBP-621831.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Skint8
Protein Name selection and upkeep of intraepithelial T cells 8
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000133268
InnateDB Gene IDBG-268493 (Skint8)
Protein Structure
UniProt Annotation
Function May act by engaging a cell surface molecule on immature T-cells in the embryonic thymus. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in skin, thymus, testis and, to a lower extent, bladder, brain, heart, kidney, mammary gland, small intestine and uterus. {ECO:0000269PubMed:18408721}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:3651523
InterPro IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013162 CD80-like, immunoglobulin C2-set
PFAM PF07679
PF07686
PF08205
PRINTS
PIRSF
SMART SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A7XV07
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 639774
UniGene Mm.248185
RefSeq NP_001093936
MGI ID
MGI Symbol Skint8
OMIM
CCDS CCDS51265
HPRD
IMGT
EMBL AL627076 EF494903 EF494904 EU099307 EU099308
GenPept ABS30725 ABS30726 ABU87905 ABU87906

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca