InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: TLR2

Summary

InnateDB Gene

IDBG-41789.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TLR2

Gene Name

toll-like receptor 2

Synonyms

CD282; TIL4

Species

Homo sapiens

Ensembl Gene

ENSG00000137462

Encoded Proteins

IDBP-41791

toll-like receptor 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

InnateDB Annotation

Summary

PMID 20505832

TLR2 plays a critical role in the ability of innate immunity to determine M. pulmonis numbers in the lung, and early after respiratory infection TLR2 recognition of M. pulmonis triggers initial cytokine responses of host cells.

PMID 20927103

TLR2 functions as a sensor of oxidation-associated molecular patterns, providing a key link connecting inflammation, oxidative stress, innate immunity and angiogenesis.

PMID 21439957

TLR1 :: TLR2 dimeric pairs recognize malarial glycosylphosphatidylinositols (GPI) to initiates intracellular signalling and the production of pro-inflammatory cytokines.

PMID 21454596

TLR2 recognizes Thermus aquaticus extracellular polysacchride, YT-1, and induces the production of cytokines TNF and IL6 in peritoneal macrophages. (Demonstrated in murine model)

PMID 21482737

TLR2::TLR6 synergistically interacts with TLR9 in lung epithelium to induce rapid pathogen killing, and can be used as a therapeutic target to treat otherwise lethal pneumonia.

PMID 21512004

TLR2 is activated by gut commensal microbe, Bacteroides fragilis, to establish host-microbial symbiosis by promoting immunological tolerance. (Demonstrated in murine model)

PMID 21566133

TLR2 and TNFSF11 signalling pathways are modulated by Porphromonas gingivalis to alter the differentiation states of osteoclasts resulting in bacteria-mediated bone loss. (Demonstrated in murine model)

PMID 21602496

TLR2 is expressed by Muller cells, principal glia of retina, and is responsible for generating robust bactericidal activity against Staphylococcus aureus and contributing to retinal innate defence.

PMID 21698237

TLR2 is required for rapid inflammasome activation in response to infection by cytosolic bacterial pathogens such as Francisella novicida. (Demonstrated in murine model)

PMID 21862586

TLR2-driven integration of inducible nitric oxide synthase (iNOS), Wnt-beta-Catenin and NOTCH1 signalling contributes to its capacity to regulate a battery of genes associated with T regulatory cell lineage commitment and towards modulation of defined set of effector functions in macrophages. (Demonstrated in murine model)

PMID 21873606

TLR2 directly recognizes glycogen, resulting in the activation of immunocytes such as macrophages to enhance the production of nitric oxide and inflammatory cytokines.

PMID 22096480

TLR2 and TLR4 are crucial for in vivo recognition of Chlamydia pneumoniae. Tlr2/4 double-deficient mice were unable to control pneumonia caused by C. pneumoniae. (Demonstrated in mice)

PMID 22102818

TLR2 signalling promotes protective vaccine-enhancing Th17 cell responses when cells are stimulated with early secreted antigenic target protein 6 (ESAT-6) expressed by the virulent Mycobacterium tuberculosis strain H37Rv but not by tuberculosis vaccine Bacillus Calmette-Guérin (BCG). (Demonstrated in mice)

PMID 22174456

TLR2 recognizes Mycobacterium tuberculosis H37Rv cell surface lipoprotein MPT83, which induces the production of TNF, IL6, and IL12B cytokines by macrophages and upregulates macrophage function. (Demonstrated in mouse)

PMID 22216191

Mycobacterium abscessus glycopeptidolipid (GPL) prevents TLR2-mediate induction of IL8 and DEFB4A in respiratory epithelial cells.

PMID 25353353

Interaction of filamentous hemagglutinin (FHA) with TLR2 induces an innate immune response against Bordetella pertussis and the TLR2-binding domain of FHA may contribute to immunoprotection against pertussis infection.

PMID 25456159

Cutaneous bacteria can negatively regulate skin-driven immune responses by inducing Gr1(+)CD11b(+) myeloid-derived suppressor cells via TLR2-6 activation.

PMID 25531754

Soluble TLR2 (sTLR2) generated by metalloproteinase activation inhibits TLR2-induced cytokine production in THP-1 cell line.

PMID 25977263

TLR10 is a functional receptor involved in the innate immune response to H. pylori infection and the TLR2/TLR10 heterodimer functions in H. pylori lipopolysaccharide recognition.

PMID 25955717

Human Cytomegalovirus (HCMV) miR-UL112-3p efficiently targets TLR2 during HCMV infection, resulting in the inhibition of TLR2-mediated NFκB signalling.

PMID 26610398

H. pylori infection induces the expression and activation of components of NLRP3 inflammasomes in neutrophils and this activation is independent of a functional type IV secretion system, TLR2 and TLR4.

PMID 26283364

Staphylococcal superantigen-like protein 3 (SSL3) interferes with TLR2 activation at two stages. First by binding to TLR2 and blocking ligand binding and second by interacting with an already formed TLR2-lipopeptide complex, thus preventing TLR heterodimerization and downstream signalling.

PMID 26310831

PELI3 is involved in endotoxin tolerance and functions as a negative regulator of TLR2/4 signalling.

InnateDB Annotation from Orthologs

Summary

PMID 18768838

[Mus musculus] Tlr2 expression in astrocytes is induced by TNF alpha and NF Kappa B-dependent pathways.

PMID 18621910

[Mus musculus] Tlr2 recognition of Staphylococcal peptidoglycan leads to induction of beta-defensin-2.

PMID 19019963

[Mus musculus] Tlr2 is involved in Respiratory syncytial virus (RSV) recognition and subsequent innate immune activation by promoting neutrophil migration and dendritic cell activation within the lung.

PMID 19865078

[Mus musculus] Tlr4, Tlr2, or Tlr3 cooperate with proteinase-activated receptors (PARs) for activation of nuclear factor-kappaB-dependent signaling in mucosal epithelial cell lines.

PMID 9751057

[Mus musculus] Tlr2 is a signaling receptor that is activated by lipopolysaccharide (LPS) in a response that depends on LPS-binding protein and is enhanced by CD14.

PMID 10364168

[Mus musculus] Tlr2 is a signal transducer for soluble Peptidoglycan and lipoteichoic acid (LTA) in addition to LPS.

PMID 10384090

[Mus musculus] Tlr2 recognizes Gram-positive bacterial cell wall components, leading to the activation of the innate immune system.

PMID 10426996

[Mus musculus] Tlr2 is a molecular link between microbial products, apoptosis, and host defense mechanisms.

PMID 20167866

[Mus musculus] TLR2/MyD88/PI3K/Rac1/Akt pathway mediates the activation of LTA-induced mitogen-activated protein kinases (MAPKs), which in turn initiates the activation of NF-kappaB, and ultimately induces cPLA2/COX-2-dependent PGE2 and IL-6 generation.

PMID 20385881

[Mus musculus] Tlr2 and Tlr4 activate murine macrophages and this is negatively regulated by a Lyn/PI3K module and promoted by SHIP1.

PMID 20407745

[Mus musculus] Tlr2 is a molecular link between increased dietary lipid intake and the regulation of glucose homeostasis, via regulation of energy substrate utilization and tissue inflammation.

PMID 20422028

[Mus musculus] Tlr2 activation induces type I interferon responses from endolysosomal compartments where it is translocated to upon ligand engagement.

PMID 20368346

[Mus musculus] Tlr2 and Myd88-dependent phosphatidylinositol 3-kinase and Rac1 activation facilitates the phagocytosis of Listeria monocytogenes by murine macrophages.

PMID 21439957

[Mus musculus] Tlr1 :: Tlr2 dimeric pairs recognize malarial glycosylphosphatidylinositols (GPI) to initiates intracellular signalling and the production of pro-inflammatory cytokines.

PMID 21454596

[Mus musculus] Tlr2 recognizes Thermus aquaticus extracellular polysacchride, YT-1, and induces the production of cytokines TNF and IL6 in peritoneal macrophages.

PMID 21482737

[Mus musculus] Tlr2::Tlr6 synergistically interacts with Tlr9 in lung epithelium to induce rapid pathogen killing, and can be used as a therapeutic target to treat otherwise lethal pneumonia.

PMID 21512004

[Mus musculus] Tlr2 is activated by gut commensal microbe, Bacteroides fragilis, to establish host-microbial symbiosis by promoting immunological tolerance.

PMID 21566133

[Mus musculus] Tlr2 and Tnfsf11 signalling pathways are modulated by Porphromonas gingivalis to alter the differentiation states of osteoclasts resulting in bacteria-mediated bone loss.

PMID 21602496

[Mus musculus] Tlr2 is expressed by Muller cells, principal glia of retina, and is responsible for generating robust bactericidal activity against Staphylococcus aureusand contributing to retinal innate defence.

PMID 21698237

[Mus musculus] Tlr2 is required for rapid inflammasome activation in response to infection by cytosolic bacterial pathogens such as Francisella novicida.

PMID 21862586

[Mus musculus] Tlr2-driven integration of inducible nitric oxide synthase (iNOS), Wnt-beta-Catenin and Notch1 signalling contributes to its capacity to regulate a battery of genes associated with T regulatory cell lineage commitment and towards modulation of defined set of effector functions in macrophages.

PMID 21873606

[Mus musculus] Tlr2 directly recognizes glycogen, resulting in the activation of immunocytes such as macrophages to enhance the production of nitric oxide and inflammatory cytokines.

PMID 22096480

[Mus musculus] Tlr2 and Tlr4 are crucial for in vivo recognition of Chlamydia pneumoniae. Tlr2/4 double-deficient mice were unable to control pneumonia caused by C. pneumoniae.

PMID 22102818

[Mus musculus] Tlr2 signalling promotes protective vaccine-enhancing Th17 cell responses when cells are stimulated with early secreted antigenic target protein 6 (ESAT-6) expressed by the virulent Mycobacterium tuberculosis strain H37Rv but not by tuberculosis vaccine Bacillus Calmette-Guérin (BCG).

PMID 22174456

[Mus musculus] Tlr2 recognizes Mycobacterium tuberculosis H37Rv cell surface lipoprotein MPT83, which induces the production of Tnf, Il6, and Il12b cytokines by macrophages and upregulates macrophage function.

PMID 22216191

[Mus musculus] Mycobacterium abscessus glycopeptidolipid (GPL) prevents Tlr2-mediate induction of Il8 and Defb4a in respiratory epithelial cells. (Demonstrated in human)

PMID 23994200

[Mus musculus] Tlr2 is expressed in the enteric nervous system (ENS) and intestinal smooth muscle layers. Its absence induces architectural and neurochemical coding changes in the ENS, leading to gut dysmotility and to higher inflammatory bowel diseases susceptibility

PMID 25423082

[Mus musculus] Salmonella enterica serovar Typhimurium �?msbB that possesses a modified lipid A triggers exacerbated colitis in the absence of Nod1 and/or Nod2, which is likely due to increased Tlr2 stimulation.

PMID 25505250

[Mus musculus] Adaptor proteins Ticam1 and Ticam2 have a novel function in Tlr2-mediated signal transduction.

PMID 25826367

[Mus musculus] Retinoic acid treatment enhances Tlr2-dependent Il10 production from T cells and this, in turn, potentiates T regulatory cell generation without the need for activation of antigen presenting cells.

PMID 25586105

[Mus musculus] Proline-proline-glutamic acid 57 (PPE57), located on the mycobacterial cell surface, induces a T helper 1 immune response via Tlr2-mediated macrophage functions.

PMID 26078314

[Mus musculus] Tlr2 is essential for the immune responses to cholera vaccination.

PMID 26283364

[Mus musculus] Staphylococcal superantigen-like protein 3 (SSL3) interferes with Tlr2 activation at two stages. First by binding to Tlr2 and blocking ligand binding and second by interacting with an already formed Tlr2-lipopeptide complex, thus preventing TLR heterodimerization and downstream signalling.

PMID 26310831

[Mus musculus] Peli3 is involved in endotoxin tolerance and functions as a negative regulator of Tlr2/4 signalling.

PMID 26423153

[Mus musculus] Cytokine activation as a result of Tlr2 stimulation is mediated by the phagosomal trafficking molecule Ap3b1 (AP-3).

Entrez Gene

Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 4:153701500-153705699

Strand

Forward strand

Band

q31.3

Transcripts

ENST00000260010

ENSP00000260010

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 52 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	52 [view]
Protein-Protein	50 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	1 [view]
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001875	lipopolysaccharide receptor activity
GO:0004872	receptor activity
GO:0004888	transmembrane signaling receptor activity
GO:0005515	protein binding
GO:0008329	signaling pattern recognition receptor activity
GO:0042497	triacyl lipopeptide binding
GO:0042498	diacyl lipopeptide binding
GO:0042834	peptidoglycan binding
GO:0046982	protein heterodimerization activity
GO:0070891	lipoteichoic acid binding
GO:0071723	lipopeptide binding

Biological Process

GO:0001666	response to hypoxia
GO:0001774	microglial cell activation
GO:0002224	toll-like receptor signaling pathway
GO:0002238	response to molecule of fungal origin
GO:0002687	positive regulation of leukocyte migration
GO:0002752	cell surface pattern recognition receptor signaling pathway
GO:0002755	MyD88-dependent toll-like receptor signaling pathway
GO:0006691	leukotriene metabolic process
GO:0006915	apoptotic process
GO:0006954	inflammatory response
GO:0006955	immune response
GO:0007165	signal transduction
GO:0007252	I-kappaB phosphorylation
GO:0008285	negative regulation of cell proliferation
GO:0009617	response to bacterium
GO:0009636	response to toxic substance
GO:0030177	positive regulation of Wnt signaling pathway
GO:0031663	lipopolysaccharide-mediated signaling pathway
GO:0032289	central nervous system myelin formation
GO:0032493	response to bacterial lipoprotein
GO:0032494	response to peptidoglycan
GO:0032496	response to lipopolysaccharide
GO:0032570	response to progesterone
GO:0032695	negative regulation of interleukin-12 production
GO:0032700	negative regulation of interleukin-17 production
GO:0032722	positive regulation of chemokine production
GO:0032728	positive regulation of interferon-beta production
GO:0032733	positive regulation of interleukin-10 production
GO:0032735	positive regulation of interleukin-12 production
GO:0032741	positive regulation of interleukin-18 production
GO:0032755	positive regulation of interleukin-6 production
GO:0032757	positive regulation of interleukin-8 production
GO:0032760	positive regulation of tumor necrosis factor production
GO:0032868	response to insulin
GO:0034123	positive regulation of toll-like receptor signaling pathway
GO:0034134	toll-like receptor 2 signaling pathway
GO:0034142	toll-like receptor 4 signaling pathway
GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124	toll-like receptor TLR6:TLR2 signaling pathway
GO:0042346	positive regulation of NF-kappaB import into nucleus
GO:0042495	detection of triacyl bacterial lipopeptide
GO:0042496	detection of diacyl bacterial lipopeptide
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process
GO:0042892	chloramphenicol transport
GO:0044130	negative regulation of growth of symbiont in host
GO:0045087	innate immune response (InnateDB)
GO:0045429	positive regulation of nitric oxide biosynthetic process
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0046209	nitric oxide metabolic process
GO:0048714	positive regulation of oligodendrocyte differentiation
GO:0050715	positive regulation of cytokine secretion
GO:0050729	positive regulation of inflammatory response
GO:0050830	defense response to Gram-positive bacterium
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process
GO:0052063	induction by symbiont of defense-related host nitric oxide production
GO:0060907	positive regulation of macrophage cytokine production
GO:0070542	response to fatty acid
GO:0071221	cellular response to bacterial lipopeptide
GO:0071223	cellular response to lipoteichoic acid
GO:0071224	cellular response to peptidoglycan
GO:0071726	cellular response to diacyl bacterial lipopeptide
GO:0071727	cellular response to triacyl bacterial lipopeptide

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0009897	external side of plasma membrane
GO:0009986	cell surface
GO:0016021	integral component of membrane
GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex
GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex
GO:0042995	cell projection
GO:0044297	cell body

Orthologs

Species

Mus musculus

Bos taurus

Gene ID

Gene Order

ENSMUSG00000027995

View Gene Order

ENSBTAG00000008008

Not yet available

Pathways

NETPATH

REACTOME

REACT_6788

MyD88:Mal cascade initiated on plasma membrane pathway

REACT_8005

Toll Like Receptor TLR1:TLR2 Cascade pathway

REACT_8006

Toll Like Receptor TLR6:TLR2 Cascade pathway

REACT_6894

Toll Like Receptor 4 (TLR4) Cascade pathway

REACT_115897

Beta defensins pathway

REACT_115846

Defensins pathway

REACT_6802

Innate Immune System pathway

REACT_7980

Toll Like Receptor 2 (TLR2) Cascade pathway

REACT_6966

Toll-Like Receptors Cascades pathway

REACT_6900

Immune System pathway

REACT_6890

Activated TLR4 signalling pathway

KEGG

hsa04620

Toll-like receptor signaling pathway pathway

hsa05140

Leishmaniasis pathway

hsa05146

Amoebiasis pathway

hsa05144

Malaria pathway

hsa05142

Chagas disease (American trypanosomiasis) pathway

hsa05145

Toxoplasmosis pathway

hsa04145

Phagosome pathway

INOH

PID NCI

toll_endogenous_pathway

Endogenous TLR signaling

Cross-References

SwissProt

O60603

TrEMBL

C6KIA6 K9MV98

UniProt Splice Variant

Entrez Gene

7097

UniGene

Hs.519033 Hs.623716

RefSeq

NM_003264 XM_005263193 XM_005263194 XM_005263195 XM_005263196 XM_005263197

HUGO

HGNC:11848

OMIM

603028

CCDS

CCDS3784

HPRD

IMGT

EMBL

AB445624 AF051152 AF502291 BC033756 CH471056 DQ012265 DQ012266 DQ012267 DQ012268 DQ012269 DQ012270 DQ012271 GQ228031 GQ228032 GQ228033 JQ481242 JQ481243 JQ481244 JQ481245 JQ481246 JQ481247 JQ481248 JQ481249 JQ481250 JQ481251 JQ481252 JQ481253 JQ481254 JQ481255 JQ481256 JQ481257 JQ481258 JQ481259 JQ481260 JQ481261 JQ481262 JQ481263 JQ481264 JQ481265 JQ481266 JQ481267 JQ481268 JQ481269 JQ481270 JQ481271 JQ481272 JQ481273 JQ481274 JQ481275 JQ481276 JQ481277 JQ481278 JQ481279 JQ481280 JQ481281 JQ481282 JQ481283 JQ481284 JQ481285 JQ481286 JQ481287 JQ481288 JQ481289 JQ481290 JQ481291 JQ481292 JQ481293 JQ481294 JQ481295 JQ481296 JQ481297 JQ481298 JQ481299 JQ481300 JQ481301 JQ481302 JQ481303 JQ481304 JQ481305 JQ481306 JQ481307 JQ481308 JQ481309 JQ481310 JQ481311 JQ481312 JQ481313 JQ481314 JQ481315 JQ481316 JQ481317 JQ481318 JQ481319 JQ481320 JQ481321 JQ481322 JQ481323 JQ481324 JQ481325 JQ481326 JQ481327 JQ481328 JQ481329 JQ481330 JQ481331 JQ481332 JQ481333 JQ481334 JQ481335 JQ481336 JQ481337 JQ481338 JQ481339 JQ481340 JQ481341 JQ481342 JQ481343 JQ481344 JQ481345 JQ481346 JQ481347 JQ481348 JQ481349 JQ481350 JQ481351 JQ481352 JQ481353 JQ481354 JQ481355 JQ481356 JQ481357 JQ481358 JQ481359 JQ481360 JQ481361 JQ481362 JQ481363 JQ481364 JQ481365 JQ481366 JQ481367 JQ481368 JQ481369 JQ481370 JQ481371 JQ481372 JQ481373 JQ481374 JQ481375 JQ481376 JQ481377 JQ481378 JQ481379 JQ481380 JQ481381 JQ481382 JQ481383 JQ481384 JQ481385 JQ481386 JQ481387 JQ481388 JQ481389 JQ481390 JQ481391 JQ481392 JQ481393 JQ481394 JQ481395 JQ481396 JQ481397 JQ481398 JQ481399 JQ481400 JQ481401 JQ481402 JQ481403 JQ481404 JQ481405 JQ481406 JQ481407 JQ481408 JQ481409 JQ481410 JQ481411 JQ481412 JQ481413 JQ481414 JQ481415 JQ481416 JQ481417 JQ481418 JQ481419 JQ481420 JQ481421 JQ481422 JQ481423 JQ481424 JQ481425 JQ481426 JQ481427 JQ481428 JQ481429 JQ481430 JQ481431 JQ481432 JQ481433 JQ481434 JQ481435 JQ481436 JQ481437 JQ481438 JQ481439 JQ481440 JQ481441 JQ481442 JQ481443 JQ481444 JQ481445 JQ481446 JQ481447 JQ481448 JQ481449 JQ481450 JQ481451 JQ481452 JQ481453 JQ481454 JQ481455 JQ481456 JQ481457 JQ481458 JQ481459 JQ481460 JQ481461 JQ481462 JQ481463 JQ481464 JQ481465 JQ481466 JQ481467 JQ481468 JQ481469 JQ481470 JQ481471 JQ481472 JQ481473 JQ481474 JQ481475 JQ481476 JQ481477 JQ481478 JQ481479 JQ481480 JQ481481 JQ481482 JQ481483 JQ481484 JQ481485 JQ481486 JQ481487 JQ481488 JQ481489 JQ481490 JQ481491 JQ481492 JQ481493 JQ481494 JQ481495 JQ481496 JQ481497 JQ481498 JQ481499 JQ481500 JQ481501 JQ481502 JQ481503 JQ481504 JQ481505 JQ481506 JQ481507 JQ481508 JQ481509 JQ481510 JQ481511 JQ481512 JQ481513 JQ481514 JQ481515 JQ481516 JQ481517 JQ481518 JQ481519 JQ481520 JQ481521 JQ481522 JQ481523 JQ481524 JQ481525 JQ481526 JQ481527 JQ481528 JQ481529 JQ481530 JQ481531 JQ481532 JQ481533 JQ481534 JQ481535 JQ481536 JQ481537 JQ481538 JQ481539 JQ481540 JQ481541 JQ481542 JQ481543 JQ481544 JQ481545 JQ481546 JQ481547 JQ481548 JQ481549 JQ481550 JQ481551 JQ481552 JQ481553 JQ481554 JQ481555 JQ481556 JQ481557 JQ481558 JQ481559 JQ481560 JQ481561 JQ481562 JQ481563 JQ481564 JQ481565 JQ481566 JQ481567 JQ481568 JQ481569 JQ481570 JQ481571 JQ481572 JQ481573 JQ481574 JQ481575 JQ481576 JQ481577 JQ481578 JQ481579 JQ481580 JQ481581 JQ481582 JQ481583 JQ481584 JQ481585 JQ481586 JQ481587 JQ481588 JQ481589 JQ481590 JQ481591 JQ481592 JQ481593 JQ481594 JQ481595 JQ481596 JQ481597 JQ481598 JQ481599 JQ481600 JQ481601 JQ481602 JQ481603 JQ481604 JQ481605 JQ481606 JQ481607 JQ481608 JQ481609 JQ481610 JQ481611 JQ481612 JQ481613 JQ481614 JQ481615 JQ481616 JQ481617 JQ481618 JQ481619 JQ481620 JQ481621 JQ481622 JQ481623 JQ481624 JQ481625 JQ481626 JQ481627 JQ481628 JQ481629 JQ481630 U88878

GenPept

AAC34133 AAC34377 AAH33756 AAM23001 AAY85644 AAY85645 AAY85646 AAY85647 AAY85648 AAY85649 AAY85650 ACS88975 ACS88976 ACS88977 AFX72318 AFX72319 AFX72320 AFX72321 AFX72322 AFX72323 AFX72324 AFX72325 AFX72326 AFX72327 AFX72328 AFX72329 AFX72330 AFX72331 AFX72332 AFX72333 AFX72334 AFX72335 AFX72336 AFX72337 AFX72338 AFX72339 AFX72340 AFX72341 AFX72342 AFX72343 AFX72344 AFX72345 AFX72346 AFX72347 AFX72348 AFX72349 AFX72350 AFX72351 AFX72352 AFX72353 AFX72354 AFX72355 AFX72356 AFX72357 AFX72358 AFX72359 AFX72360 AFX72361 AFX72362 AFX72363 AFX72364 AFX72365 AFX72366 AFX72367 AFX72368 AFX72369 AFX72370 AFX72371 AFX72372 AFX72373 AFX72374 AFX72375 AFX72376 AFX72377 AFX72378 AFX72379 AFX72380 AFX72381 AFX72382 AFX72383 AFX72384 AFX72385 AFX72386 AFX72387 AFX72388 AFX72389 AFX72390 AFX72391 AFX72392 AFX72393 AFX72394 AFX72395 AFX72396 AFX72397 AFX72398 AFX72399 AFX72400 AFX72401 AFX72402 AFX72403 AFX72404 AFX72405 AFX72406 AFX72407 AFX72408 AFX72409 AFX72410 AFX72411 AFX72412 AFX72413 AFX72414 AFX72415 AFX72416 AFX72417 AFX72418 AFX72419 AFX72420 AFX72421 AFX72422 AFX72423 AFX72424 AFX72425 AFX72426 AFX72427 AFX72428 AFX72429 AFX72430 AFX72431 AFX72432 AFX72433 AFX72434 AFX72435 AFX72436 AFX72437 AFX72438 AFX72439 AFX72440 AFX72441 AFX72442 AFX72443 AFX72444 AFX72445 AFX72446 AFX72447 AFX72448 AFX72449 AFX72450 AFX72451 AFX72452 AFX72453 AFX72454 AFX72455 AFX72456 AFX72457 AFX72458 AFX72459 AFX72460 AFX72461 AFX72462 AFX72463 AFX72464 AFX72465 AFX72466 AFX72467 AFX72468 AFX72469 AFX72470 AFX72471 AFX72472 AFX72473 AFX72474 AFX72475 AFX72476 AFX72477 AFX72478 AFX72479 AFX72480 AFX72481 AFX72482 AFX72483 AFX72484 AFX72485 AFX72486 AFX72487 AFX72488 AFX72489 AFX72490 AFX72491 AFX72492 AFX72493 AFX72494 AFX72495 AFX72496 AFX72497 AFX72498 AFX72499 AFX72500 AFX72501 AFX72502 AFX72503 AFX72504 AFX72505 AFX72506 AFX72507 AFX72508 AFX72509 AFX72510 AFX72511 AFX72512 AFX72513 AFX72514 AFX72515 AFX72516 AFX72517 AFX72518 AFX72519 AFX72520 AFX72521 AFX72522 AFX72523 AFX72524 AFX72525 AFX72526 AFX72527 AFX72528 AFX72529 AFX72530 AFX72531 AFX72532 AFX72533 AFX72534 AFX72535 AFX72536 AFX72537 AFX72538 AFX72539 AFX72540 AFX72541 AFX72542 AFX72543 AFX72544 AFX72545 AFX72546 AFX72547 AFX72548 AFX72549 AFX72550 AFX72551 AFX72552 AFX72553 AFX72554 AFX72555 AFX72556 AFX72557 AFX72558 AFX72559 AFX72560 AFX72561 AFX72562 AFX72563 AFX72564 AFX72565 AFX72566 AFX72567 AFX72568 AFX72569 AFX72570 AFX72571 AFX72572 AFX72573 AFX72574 AFX72575 AFX72576 AFX72577 AFX72578 AFX72579 AFX72580 AFX72581 AFX72582 AFX72583 AFX72584 AFX72585 AFX72586 AFX72587 AFX72588 AFX72589 AFX72590 AFX72591 AFX72592 AFX72593 AFX72594 AFX72595 AFX72596 AFX72597 AFX72598 AFX72599 AFX72600 AFX72601 AFX72602 AFX72603 AFX72604 AFX72605 AFX72606 AFX72607 AFX72608 AFX72609 AFX72610 AFX72611 AFX72612 AFX72613 AFX72614 AFX72615 AFX72616 AFX72617 AFX72618 AFX72619 AFX72620 AFX72621 AFX72622 AFX72623 AFX72624 AFX72625 AFX72626 AFX72627 AFX72628 AFX72629 AFX72630 AFX72631 AFX72632 AFX72633 AFX72634 AFX72635 AFX72636 AFX72637 AFX72638 AFX72639 AFX72640 AFX72641 AFX72642 AFX72643 AFX72644 AFX72645 AFX72646 AFX72647 AFX72648 AFX72649 AFX72650 AFX72651 AFX72652 AFX72653 AFX72654 AFX72655 AFX72656 AFX72657 AFX72658 AFX72659 AFX72660 AFX72661 AFX72662 AFX72663 AFX72664 AFX72665 AFX72666 AFX72667 AFX72668 AFX72669 AFX72670 AFX72671 AFX72672 AFX72673 AFX72674 AFX72675 AFX72676 AFX72677 AFX72678 AFX72679 AFX72680 AFX72681 AFX72682 AFX72683 AFX72684 AFX72685 AFX72686 AFX72687 AFX72688 AFX72689 AFX72690 AFX72691 AFX72692 AFX72693 AFX72694 AFX72695 AFX72696 AFX72697 AFX72698 AFX72699 AFX72700 AFX72701 AFX72702 AFX72703 AFX72704 AFX72705 AFX72706 BAG55021 EAX04952 EAX04953

RNA Seq Atlas

7097