InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: RUVBL1

Summary

InnateDB Gene

IDBG-55108.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RUVBL1

Gene Name

RuvB-like 1 (E. coli)

Synonyms

ECP54; INO80H; NMP238; PONTIN; Pontin52; RVB1; TIH1; TIP49; TIP49A

Species

Homo sapiens

Ensembl Gene

ENSG00000175792

Encoded Proteins

IDBP-55110

RuvB-like 1 (E. coli)

IDBP-478344

RuvB-like 1 (E. coli)

IDBP-474530

RuvB-like 1 (E. coli)

IDBP-485369

RuvB-like 1 (E. coli)

IDBP-719730

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:128064778-128153914

Strand

Reverse strand

Band

q21.3

Transcripts

ENST00000322623	ENSP00000318297
ENST00000472125	ENSP00000417370
ENST00000464873	ENSP00000420738
ENST00000478892	ENSP00000417254
ENST00000480616
ENST00000478243
ENST00000585057	ENSP00000463669
ENST00000582176

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 207 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	208 [view]
Protein-Protein	205 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003678	DNA helicase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0009378	four-way junction helicase activity
GO:0043141	ATP-dependent 5'-3' DNA helicase activity

Biological Process

GO:0006281	DNA repair
GO:0006310	DNA recombination
GO:0006325	chromatin organization
GO:0006334	nucleosome assembly
GO:0006351	transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0007067	mitotic nuclear division
GO:0007283	spermatogenesis
GO:0032508	DNA duplex unwinding
GO:0034080	centromere-specific nucleosome assembly
GO:0040008	regulation of growth
GO:0043967	histone H4 acetylation
GO:0043968	histone H2A acetylation

Cellular Component

GO:0000812	Swr1 complex
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0005815	microtubule organizing center
GO:0016020	membrane
GO:0016363	nuclear matrix
GO:0030529	ribonucleoprotein complex
GO:0031011	Ino80 complex
GO:0035267	NuA4 histone acetyltransferase complex
GO:0043231	intracellular membrane-bounded organelle
GO:0043234	protein complex
GO:0070062	extracellular vesicular exosome
GO:0071339	MLL1 complex