Version 5.4
Bos taurus Gene: GYS1
Summary
InnateDB Gene IDBG-640353.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GYS1
Gene Name Glycogen
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000039958
Encoded Proteins
IDBP-692620
Glycogen
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104812:
The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:55996079-56012727
Strand Reverse strand
Band
Transcripts
ENSBTAT00000007423 ENSBTAP00000007423
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004373 glycogen (starch) synthase activity
GO:0005515 protein binding
GO:0016740 transferase activity
GO:0016757 transferase activity, transferring glycosyl groups
GO:0019901 protein kinase binding
GO:0061547 glycogen synthase activity, transferring glucose-1-phosphate
Biological Process
GO:0005978 glycogen biosynthetic process
GO:0007507 heart development
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0016234 inclusion body
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000104812
View Gene Order
ENSMUSG00000003865
View Gene Order
Pathways
NETPATH
REACTOME
REACT_213093
Glycogen synthesis pathway
REACT_221274
Metabolism of carbohydrates pathway
REACT_219973
Myoclonic epilepsy of Lafora pathway
REACT_211129
Glycogen storage diseases pathway
REACT_224672
Glucose metabolism pathway
REACT_219139
Metabolism pathway
REACT_207087
Disease pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_6
KitReceptor pathway
REACTOME
REACT_200783
Myoclonic epilepsy of Lafora pathway
REACT_169208
Glycogen synthesis pathway
REACT_474
Metabolism of carbohydrates pathway
REACT_111217
Metabolism pathway
REACT_116125
Disease pathway
REACT_723
Glucose metabolism pathway
REACT_200833
Glycogen storage diseases pathway
REACT_189085
Disease pathway
REACT_261601
Glucose metabolism pathway
REACT_188937
Metabolism pathway
REACT_188939
Glycogen synthesis pathway
REACT_203949
Glycogen storage diseases pathway
REACT_203841
Myoclonic epilepsy of Lafora pathway
REACT_248571
Metabolism of carbohydrates pathway
KEGG
hsa04910
Insulin signaling pathway pathway
hsa00500
Starch and sucrose metabolism pathway
mmu04910
Insulin signaling pathway pathway
mmu00500
Starch and sucrose metabolism pathway
INOH
INOH website
Insulin receptor signaling pathway
INOH website
Insulin receptor signaling pathway
PID NCI
insulin_glucose_pathway
Insulin-mediated glucose transport
Cross-References
SwissProt A7MB78
TrEMBL
UniProt Splice Variant
Entrez Gene 786335
UniGene Bt.102939 Bt.105158 Bt.107167 Bt.37378
RefSeq NM_001024515 NM_001101299 XM_005219383
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC151381
GenPept AAI51382
RNA Seq Atlas 511047 786335
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca