Version 5.4
| Bos taurus Gene: AP2A1 | |||||||||||
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| Summary | |||||||||||
| InnateDB Gene | IDBG-640728.3 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | AP2A1 | ||||||||||
| Gene Name | Uncharacterized protein | ||||||||||
| Synonyms | |||||||||||
| Species | Bos taurus | ||||||||||
| Ensembl Gene | ENSBTAG00000019180 | ||||||||||
| Encoded Proteins |
Uncharacterized protein
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| Protein Structure | |||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| Entrez Gene | |||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196961:
This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome 18:56592974-56620907 | ||||||||||
| Strand | Forward strand | ||||||||||
| Band | |||||||||||
| Transcripts |
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| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 43 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||||
| NETPATH |
EGFR1 pathway
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| REACTOME |
MHC class II antigen presentation pathway
Retrograde neurotrophin signalling pathway
EGFR downregulation pathway
Signaling by EGFR pathway
Nef Mediated CD8 Down-regulation pathway
Nef Mediated CD4 Down-regulation pathway
Trafficking of GluR2-containing AMPA receptors pathway
Trafficking of AMPA receptors pathway
Recycling pathway of L1 pathway
L1CAM interactions pathway
PCP/CE pathway pathway
Developmental Biology pathway
Signalling by NGF pathway
Signaling by EGFR in Cancer pathway
WNT5A-dependent internalization of FZD4 pathway
beta-catenin independent WNT signaling pathway
Signaling by Wnt pathway
Neuronal System pathway
Axon guidance pathway
Signal Transduction pathway
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters pathway
Adaptive Immune System pathway
Immune System pathway
NGF signalling via TRKA from the plasma membrane pathway
Transmission across Chemical Synapses pathway
EPH-ephrin mediated repulsion of cells pathway
HIV Infection pathway
EPH-Ephrin signaling pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
The role of Nef in HIV-1 replication and disease pathogenesis pathway
Host Interactions of HIV factors pathway
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity pathway
Disease pathway
WNT5A-dependent internalization of FZD4 pathway
EGFR downregulation pathway
Disease pathway
Signaling by Wnt pathway
Recycling pathway of L1 pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
beta-catenin independent WNT signaling pathway
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity pathway
Immune System pathway
Retrograde neurotrophin signalling pathway
PCP/CE pathway pathway
MHC class II antigen presentation pathway
Signaling by EGFR pathway
Axon guidance pathway
L1CAM interactions pathway
Signalling by NGF pathway
Adaptive Immune System pathway
Neuronal System pathway
Developmental Biology pathway
Trafficking of GluR2-containing AMPA receptors pathway
NGF signalling via TRKA from the plasma membrane pathway
Signal Transduction pathway
Trafficking of AMPA receptors pathway
Transmission across Chemical Synapses pathway
Signaling by EGFR in Cancer pathway
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| KEGG |
Endocytosis pathway
Huntington's disease pathway
Huntington's disease pathway
Endocytosis pathway
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| INOH | |||||||||||
| PID NCI |
Arf1 pathway
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| Cross-References | |||||||||||
| SwissProt | |||||||||||
| TrEMBL | E1BMW2 Q1JPJ7 | ||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | |||||||||||
| UniGene | |||||||||||
| RefSeq | |||||||||||
| HUGO | |||||||||||
| OMIM | |||||||||||
| CCDS | |||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| EMBL | BT025356 DAAA02047483 DAAA02047484 DAAA02047485 | ||||||||||
| GenPept | ABF57312 | ||||||||||
| RNA Seq Atlas | |||||||||||