InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sp1

Summary

InnateDB Protein

IDBP-188609.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sp1

Protein Name

trans-acting transcription factor 1

Synonyms

1110003E12Rik; AA450830; AI845540; Sp1-1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000001326

InnateDB Gene

IDBG-188607 (Sp1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 60 experimentally validated interaction(s) in this database.
They are also associated with 256 interaction(s) predicted by orthology.

Experimentally validated
Total	60 [view]
Protein-Protein	41 [view]
Protein-DNA	19 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	256 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
GO:0000987	core promoter proximal region sequence-specific DNA binding
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003690	double-stranded DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0008134	transcription factor binding
GO:0035035	histone acetyltransferase binding
GO:0035326	enhancer binding
GO:0042803	protein homodimerization activity
GO:0042826	histone deacetylase binding
GO:0043565	sequence-specific DNA binding
GO:0044212	transcription regulatory region DNA binding
GO:0046872	metal ion binding
GO:0071837	HMG box domain binding

Biological Process

GO:0001503	ossification
GO:0001701	in utero embryonic development
GO:0001829	trophectodermal cell differentiation
GO:0001889	liver development
GO:0001892	embryonic placenta development
GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0030219	megakaryocyte differentiation
GO:0030324	lung development
GO:0043353	enucleate erythrocyte differentiation
GO:0043923	positive regulation by host of viral transcription
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048596	embryonic camera-type eye morphogenesis
GO:0048706	embryonic skeletal system development
GO:0060136	embryonic process involved in female pregnancy
GO:0060216	definitive hemopoiesis