InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CSNK2A1

Summary

InnateDB Protein

IDBP-228734.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CSNK2A1

Protein Name

casein kinase 2, alpha 1 polypeptide

Synonyms

CK2A1; CKII; CSNK2A3;

Species

Homo sapiens

Ensembl Protein

ENSP00000383086

InnateDB Gene

IDBG-37787 (CSNK2A1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 440 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Experimentally validated
Total	440 [view]
Protein-Protein	433 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	3 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0006468

protein phosphorylation

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR002575 Aminoglycoside phosphotransferase
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714
PF01636

PRINTS

PR00109

PIRSF

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt