Version 5.4
Homo sapiens Protein: TP53
Summary
InnateDB Protein IDBP-480240.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TP53
Protein Name tumor protein p53
Synonyms BCC7; LFS1; P53; TRP53;
Species Homo sapiens
Ensembl Protein ENSP00000426252
InnateDB Gene IDBG-26364 (TP53)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1328 experimentally validated interaction(s) in this database.
They are also associated with 85 interaction(s) predicted by orthology.
Experimentally validated
Total 1328 [view]
Protein-Protein 1244 [view]
Protein-DNA 66 [view]
Protein-RNA 0
DNA-DNA 18 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 85 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0044212 transcription regulatory region DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0045087 innate immune response (InnateDB)
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR008967 p53-like transcription factor, DNA-binding
IPR011615 p53, DNA-binding domain
IPR013872 p53 transactivation domain
PFAM PF00870
PF08563
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q6IT77
UniProt Splice Variant
Entrez Gene 7157
UniGene Hs.743051
RefSeq
HUGO HGNC:11998
OMIM 191170
CCDS
HPRD 01859
IMGT
EMBL AC007421 AC087388 AY627884 DQ812984 JF923567 JQ751923 JQ751928 JQ751931 JQ751933 JQ751934 JQ751936 JQ751938 JQ751939 JQ751941 JQ751947 JQ751948 JQ751952 JQ751957 JQ751958 JQ751959 JQ751961 JQ751965 JQ751966 JQ751971 JQ751972 JQ751975 JQ751979 JQ751988 JQ751993 JQ751994 JQ752001 JQ752012 JQ752017 JQ752018 JQ752019 JQ752021 JQ752023 JQ752026 JQ752027 JQ752030 JQ752033 JQ752034 JQ752035 JQ752046 JQ752047 JQ752063 JQ752064 JQ752072 JQ752073 JQ752086 JQ752087 JQ752088 JQ752089 JQ752094 JQ752096 JQ752097 JQ752098 JQ752103 JQ752104 JQ752105 JQ752106 JQ752117 JQ752118 JQ752119 JQ752120 JQ752123 JQ752124 JQ752125 JQ752126 JQ752131 JQ752137 JQ752138 JQ752139 JQ752142 JQ752144 JQ752147 JQ752154 JQ752156 JQ752162 JQ752164 JQ752171 JQ752174 JQ752179 JQ752184 JQ752186 JQ752191 JQ752194 JQ752200 JQ752202 JQ752204 JQ752205 JQ752208 JQ752209 JQ752210 JQ752211 JQ752212 JQ752216 JQ752219 JQ752220 JQ752224 JQ752226 JQ752227 JQ752231 JQ752232
GenPept AAT40418 ABG67755 AEQ16481 AGA63129 AGA63134 AGA63137 AGA63139 AGA63140 AGA63142 AGA63144 AGA63145 AGA63147 AGA63153 AGA63154 AGA63158 AGA63163 AGA63164 AGA63165 AGA63167 AGA63171 AGA63172 AGA63176 AGA63177 AGA63180 AGA63184 AGA63193 AGA63198 AGA63199 AGA63206 AGA63217 AGA63222 AGA63223 AGA63224 AGA63226 AGA63228 AGA63231 AGA63232 AGA63235 AGA63238 AGA63239 AGA63240 AGA63251 AGA63252 AGA63268 AGA63269 AGA63277 AGA63278 AGA63291 AGA63292 AGA63293 AGA63294 AGA63299 AGA63301 AGA63302 AGA63303 AGA63308 AGA63309 AGA63310 AGA63311 AGA63322 AGA63323 AGA63324 AGA63325 AGA63328 AGA63329 AGA63330 AGA63331 AGA63336 AGA63342 AGA63343 AGA63344 AGA63347 AGA63349 AGA63352 AGA63359 AGA63361 AGA63367 AGA63369 AGA63376 AGA63379 AGA63384 AGA63389 AGA63391 AGA63396 AGA63399 AGA63405 AGA63407 AGA63409 AGA63410 AGA63413 AGA63414 AGA63415 AGA63416 AGA63417 AGA63421 AGA63424 AGA63425 AGA63429 AGA63431 AGA63432 AGA63436 AGA63437

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca