InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pde6h

Summary

InnateDB Protein

IDBP-540041.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pde6h

Protein Name

phosphodiesterase 6H, cGMP-specific, cone, gamma

Synonyms

A930033D18Rik; PDEgamma;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000119246

InnateDB Gene

IDBG-195204 (Pde6h)

Protein Structure

UniProt Annotation

Function

Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0030553	cGMP binding
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity

Biological Process

GO:0000187	activation of MAPK activity
GO:0007601	visual perception
GO:0008152	metabolic process
GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
GO:0050896	response to stimulus