Version 5.4
Homo sapiens Protein: COIL
Summary
InnateDB Protein IDBP-60270.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COIL
Protein Name coilin
Synonyms CLN80; p80-coilin;
Species Homo sapiens
Ensembl Protein ENSP00000240316
InnateDB Gene IDBG-60268 (COIL)
Protein Structure
UniProt Annotation
Function Component of nuclear coiled bodies, also known as Cajal bodies or CBs, which are involved in the modification and assembly of nucleoplasmic snRNPs. {ECO:0000269PubMed:7679389}.
Subcellular Localization Nucleus {ECO:0000269PubMed:7679389}. Nucleus, Cajal body {ECO:0000269PubMed:7679389}.
Disease Associations
Tissue Specificity Found in all the cell types examined.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 93 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 93 [view]
Protein-Protein 90 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0015036 disulfide oxidoreductase activity
GO:0042802 identical protein binding
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0001674 female germ cell nucleus
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0015030 Cajal body
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P38432
PhosphoSite PhosphoSite-P38432
TrEMBL
UniProt Splice Variant
Entrez Gene 8161
UniGene Hs.708320
RefSeq NP_004636
HUGO HGNC:2184
OMIM 600272
CCDS CCDS11592
HPRD 02605
IMGT
EMBL AC004584 AK313616 BC010385 CH471109 M58411 U06632
GenPept AAA36412 AAB81550 AAH10385 BAG36378 EAW94522

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca