InnateDB Protein
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IDBP-622450.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Gpr77
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Protein Name
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G protein-coupled receptor 77
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000133056
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InnateDB Gene
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IDBG-146283 (Gpr77)
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Protein Structure
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Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
|
Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
GO:0006935
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chemotaxis
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GO:0006954
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inflammatory response
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GO:0007186
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G-protein coupled receptor signaling pathway
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GO:0032720
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negative regulation of tumor necrosis factor production
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GO:0045087
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innate immune response (InnateDB)
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GO:0050679
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positive regulation of epithelial cell proliferation
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GO:0070374
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positive regulation of ERK1 and ERK2 cascade
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GO:0090024
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negative regulation of neutrophil chemotaxis
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GO:1900165
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negative regulation of interleukin-6 secretion
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GO:2000482
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regulation of interleukin-8 secretion
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Cellular Component |
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PDB ID |
MGI:2442013
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InterPro |
IPR000276
G protein-coupled receptor, rhodopsin-like
IPR001274
C5a1/C5a2 anaphylatoxin chemotactic receptor
IPR017452
GPCR, rhodopsin-like, 7TM
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PFAM |
PF00001
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PRINTS |
PR00237
PR00426
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PIRSF |
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SMART |
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TIGRFAMs |
|
Modification |
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SwissProt |
Q8BW93
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PhosphoSite |
PhosphoSite-
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TrEMBL |
E9PVQ2
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UniProt Splice Variant |
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Entrez Gene |
319430
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UniGene |
Mm.239570
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RefSeq |
NP_795886
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MGI ID |
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MGI Symbol |
C5ar2
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OMIM |
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CCDS |
CCDS52037
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HPRD |
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IMGT |
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EMBL |
AC156630
AK053187
AK160050
BC137941
BC145834
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GenPept |
AAI37942
AAI45835
BAC35303
BAE35590
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