Mus musculus Protein: Sp1
Summary
InnateDB Protein IDBP-625974.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sp1
Protein Name trans-acting transcription factor 1
Synonyms 1110003E12Rik; AA450830; AI845540; Sp1-1;
Species Mus musculus
Ensembl Protein ENSMUSP00000127445
InnateDB Gene IDBG-188607 (Sp1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 60 experimentally validated interaction(s) in this database.
They are also associated with 256 interaction(s) predicted by orthology.
Experimentally validated
Total 60 [view]
Protein-Protein 41 [view]
Protein-DNA 19 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 256 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0035035 histone acetyltransferase binding
GO:0035326 enhancer binding
GO:0042803 protein homodimerization activity
GO:0042826 histone deacetylase binding
GO:0043565 sequence-specific DNA binding
GO:0071837 HMG box domain binding
Biological Process
GO:0001503 ossification
GO:0001701 in utero embryonic development
GO:0001829 trophectodermal cell differentiation
GO:0001889 liver development
GO:0001892 embryonic placenta development
GO:0006355 regulation of transcription, DNA-templated
GO:0030219 megakaryocyte differentiation
GO:0030324 lung development
GO:0043353 enucleate erythrocyte differentiation
GO:0043923 positive regulation by host of viral transcription
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048596 embryonic camera-type eye morphogenesis
GO:0048706 embryonic skeletal system development
GO:0060136 embryonic process involved in female pregnancy
GO:0060216 definitive hemopoiesis
Cellular Component
GO:0005634 nucleus
GO:0032993 protein-DNA complex
Protein Structure and Domains
PDB ID MGI:98372
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9Q2V3
UniProt Splice Variant
Entrez Gene 20683
UniGene Mm.4618
RefSeq
MGI ID
MGI Symbol Sp1
OMIM
CCDS
HPRD
IMGT
EMBL AC137156
GenPept