InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: CD9

Summary

InnateDB Protein

IDBP-692797.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CD9

Protein Name

CD9 antigen

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000019643

InnateDB Gene

IDBG-640522 (CD9)

Protein Structure

UniProt Annotation

Function

Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion (By similarity). {ECO:0000250}.

Subcellular Localization

Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Detected in cornea, and at low levels in neuroretina and ciliary epithelium cells. {ECO:0000269PubMed:1339429}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0006928	cellular component movement
GO:0007155	cell adhesion
GO:0007338	single fertilization
GO:0007342	fusion of sperm to egg plasma membrane
GO:0008285	negative regulation of cell proliferation
GO:0030913	paranodal junction assembly

Cellular Component

GO:0005615	extracellular space
GO:0005886	plasma membrane
GO:0009897	external side of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome