InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.36811

Summary

InnateDB Protein

IDBP-696751.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.36811

Protein Name

arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1

Synonyms

DDEF1;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000045295

InnateDB Gene

IDBG-644126 (BT.36811)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 46 interaction(s) predicted by orthology.

Predicted by orthology
Total	46 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
GO:0008060	ARF GTPase activator activity
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

Biological Process

GO:0032312	regulation of ARF GTPase activity
GO:0043547	positive regulation of GTPase activity
GO:0060271	cilium morphogenesis

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR001164 Arf GTPase activating protein
IPR001452 SH3 domain
IPR001849 Pleckstrin homology domain
IPR002110 Ankyrin repeat
IPR011511 Variant SH3 domain
IPR020683 Ankyrin repeat-containing domain

PFAM