InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Agfg1

Summary

InnateDB Protein

IDBP-790449.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Agfg1

Protein Name

ArfGAP with FG repeats 1

Synonyms

AU045498; C130049H11Rik; C85612; D730048C23Rik; Hrb; RAB; Rip;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000140785

InnateDB Gene

IDBG-174169 (Agfg1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0008060	ARF GTPase activator activity
GO:0008270	zinc ion binding

Biological Process

GO:0001675	acrosome assembly
GO:0006810	transport
GO:0007275	multicellular organismal development
GO:0007289	spermatid nucleus differentiation
GO:0032312	regulation of ARF GTPase activity
GO:0043547	positive regulation of GTPase activity
GO:0045109	intermediate filament organization

Cellular Component

GO:0005634	nucleus
GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0042995	cell projection
GO:0043025	neuronal cell body

Protein Structure and Domains

PDB ID

MGI:1333754

InterPro

IPR001164 Arf GTPase activating protein

PFAM

PF01412

PRINTS

PR00405

PIRSF

SMART

SM00105

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

15463

UniGene

RefSeq

XP_006496493

MGI ID

MGI Symbol

Agfg1

OMIM

CCDS

HPRD

IMGT

EMBL

AF057287 AK029917 AK048326 AK049400 BC031154

GenPept

AAC97477 AAH31154 BAC26675 BAC33303 BAC33736