Version 5.4
Bos taurus Gene: AGFG1
Summary
InnateDB Gene IDBG-644263.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AGFG1
Gene Name Arf-GAP domain and FG repeat-containing protein 1
Synonyms HRB
Species Bos taurus
Ensembl Gene ENSBTAG00000021323
Encoded Proteins
IDBP-696893
Arf-GAP domain and FG repeats-containing protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000173744:
The protein encoded by this gene is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. The encoded protein binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target, and is required for the nuclear export of Rev-directed RNAs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:116441987-116516520
Strand Forward strand
Band
Transcripts
ENSBTAT00000028427 ENSBTAP00000028427
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0008060 ARF GTPase activator activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0001675 acrosome assembly
GO:0006810 transport
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0007289 spermatid nucleus differentiation
GO:0030154 cell differentiation
GO:0032312 regulation of ARF GTPase activity
GO:0043547 positive regulation of GTPase activity
GO:0045109 intermediate filament organization
Cellular Component
GO:0005634 nucleus
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0031410 cytoplasmic vesicle
GO:0042995 cell projection
GO:0043025 neuronal cell body
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000173744
View Gene Order
ENSMUSG00000026159
View Gene Order
Cross-References
SwissProt Q2TA45
TrEMBL
UniProt Splice Variant
Entrez Gene 536149
UniGene Bt.41634
RefSeq NM_001038171 XM_005202958
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC111120
GenPept AAI11121
RNA Seq Atlas 536149

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca