Version 5.4
Bos taurus Protein: AGFG1
Summary
InnateDB Protein IDBP-696893.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AGFG1
Protein Name Arf-GAP domain and FG repeats-containing protein 1
Synonyms HRB;
Species Bos taurus
Ensembl Protein ENSBTAP00000028427
InnateDB Gene IDBG-644263 (AGFG1)
Protein Structure
UniProt Annotation
Function Required for vesicle docking or fusion during acrosome biogenesis. May play a role in RNA trafficking or localization (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0008060 ARF GTPase activator activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0001675 acrosome assembly
GO:0006810 transport
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0007289 spermatid nucleus differentiation
GO:0030154 cell differentiation
GO:0032312 regulation of ARF GTPase activity
GO:0043547 positive regulation of GTPase activity
GO:0045109 intermediate filament organization
Cellular Component
GO:0005634 nucleus
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0031410 cytoplasmic vesicle
GO:0042995 cell projection
GO:0043025 neuronal cell body
Protein Structure and Domains
PDB ID
InterPro IPR001164 Arf GTPase activating protein
PFAM PF01412
PRINTS PR00405
PIRSF
SMART SM00105
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2TA45
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 536149
UniGene Bt.41634
RefSeq NP_001033260
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC111120
GenPept AAI11121

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca