|
InnateDB Group ID
|
216065
|
|
Short name
|
NFKB1 :: BIRC3
|
|
Full name
|
NFKB1 physically interacts with BIRC3
|
|
Interaction type
|
physical interaction
|
|
Participant 1
|
|
Molecule:
|
IDBG-31974
|
|
Molecule type:
|
protein
|
|
Species:
|
Homo sapiens
|
|
HUGO:
|
NFKB1
|
|
Full name:
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
|
|
Direction:
|
input
|
|
Biological role:
|
unspecified
|
|
Participant 2
|
|
Molecule:
|
IDBG-69045
|
|
Molecule type:
|
dna
|
|
Species:
|
Homo sapiens
|
|
HUGO:
|
BIRC3
|
|
Full name:
|
baculoviral IAP repeat containing 3
|
|
Direction:
|
input
|
|
Biological role:
|
unspecified
|
|
InnateDB ID
|
IDB-115820.2
|
|
Last Modified
|
2010-03-07
|
|
Review status
|
reviewed
[Report errors or provide feedback]
|
|
Source database
|
INNATEDB
|
|
Source database ID
|
IDB-115820
|
|
PMID
|
15494311
|
|
Interaction detection method
|
chromatin immunoprecipitation assays |
|
Host system
|
invitro |
|
Host organism
|
Homo sapiens |
|
Cell status
|
cell line |
|
Cell line
|
DU 145 |
|
Cell type
|
epithelial cell |
|
Tissue type
|
prostate cancer cell line |
|
Comment
|
A constitutive association was observed. |
|
Participants
|
|
Participant Identification Method |
Experimental Role |
Participant Accession |
| 1) NFKB1 |
identification by antibody |
neutral component |
|
| 2) BIRC3 |
nucleotide sequence identification |
neutral component |
|
|
|
InnateDB ID
|
IDB-116646.2
|
|
Last Modified
|
2010-03-07
|
|
Review status
|
reviewed
[Report errors or provide feedback]
|
|
Source database
|
INNATEDB
|
|
Source database ID
|
IDB-116646
|
|
PMID
|
16982744
|
|
Interaction detection method
|
electrophoretic mobility supershift assay |
|
Host system
|
invitro |
|
Host organism
|
Homo sapiens |
|
Cell status
|
cell line |
|
Cell line
|
HT-1080 |
|
Cell type
|
epithelial cell |
|
Tissue type
|
connective tissue |
|
Comment
|
Putative NFKB Site1 in BIRC3 showed high affinity for NFKB1 |
|
Participants
|
|
Participant Identification Method |
Experimental Role |
Participant Accession |
| 1) NFKB1 |
western blot |
neutral component |
|
| 2) BIRC3 |
autoradiography |
neutral component |
|
|
|
InnateDB ID
|
IDB-1731151.1
|
|
Last Modified
|
2014-11-29
|
|
Review status
|
Unreviewed by InnateDB
[Report errors or provide feedback]
|
|
Source database
|
BIND
|
|
Source database ID
|
182690
|
|
PMID
|
15494311
|
|
Interaction detection method
|
cross-linking study |
|
Host system
|
invitro |
|
Host organism
|
|
|
Cell status
|
|
|
Cell line
|
|
|
Cell type
|
|
|
Tissue type
|
|
|
Comment
|
|
|
Participants
|
|
Participant Identification Method |
Experimental Role |
Participant Accession |
| 1) BIRC3 |
|
prey |
NC_000011 |
| 2) NFKB1 |
|
bait |
NP_003989 |
|
|
|
|
Version 5.4