Version 5.4
Homo sapiens Gene: HMHA1
Summary
InnateDB Gene IDBG-13714.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HMHA1
Gene Name histocompatibility (minor) HA-1
Synonyms ARHGAP45; HA-1; HLA-HA1
Species Homo sapiens
Ensembl Gene ENSG00000180448
Encoded Proteins
IDBP-13716
histocompatibility (minor) HA-1
IDBP-603714
histocompatibility (minor) HA-1
IDBP-593277
histocompatibility (minor) HA-1
IDBP-765962
IDBP-765542
IDBP-762007
IDBP-761592
IDBP-807690
histocompatibility (minor) HA-1
IDBP-761877
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:1065923-1086628
Strand Forward strand
Band p13.3
Transcripts
ENST00000313093 ENSP00000316772
ENST00000539243 ENSP00000439601
ENST00000543365 ENSP00000438979
ENST00000591293
ENST00000590577 ENSP00000468607
ENST00000586866 ENSP00000468615
ENST00000590512
ENST00000592335
ENST00000590214 ENSP00000466401
ENST00000586937
ENST00000587602 ENSP00000466365
ENST00000586378
ENST00000592297
ENST00000591169 ENSP00000484008
ENST00000586033
ENST00000587186 ENSP00000467741
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0046872 metal ion binding
Biological Process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0035556 intracellular signal transduction
GO:0043547 positive regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005622 intracellular
GO:0005829 cytosol
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000035697
View Gene Order
ENSBTAG00000020772
Not yet available
Pathways
NETPATH
REACTOME
REACT_11051
Rho GTPase cycle pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_111102
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL K7ES92
UniProt Splice Variant
Entrez Gene 23526
UniGene Hs.465521
RefSeq NM_001282334 NM_001258328 NM_001282335 NM_012292 XM_006722713
HUGO HGNC:17102
OMIM 601155
CCDS CCDS74243 CCDS32863 CCDS58637 CCDS74242
HPRD 03097
IMGT
EMBL AC004151 AC011558 AC093066
GenPept
RNA Seq Atlas 23526

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca