Version 5.4
| Mus musculus Gene: Ap4s1 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-138299.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Ap4s1 | ||||||||
| Gene Name | adaptor-related protein complex AP-4, sigma 1 | ||||||||
| Synonyms | AI314282 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000020955 | ||||||||
| Encoded Proteins |
adaptor-related protein complex AP-4, sigma 1
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100478:
This gene encodes a member of the adaptor complexes small subunit protein family. These proteins are components of the heterotetrameric adaptor protein complexes, which play important roles in the secretory and endocytic pathways by mediating vesicle formation and sorting of integral membrane proteins. The encoded protein is the small subunit of adaptor protein complex-4, which is associated with both clathrin- and nonclathrin-coated vesicles. Mutations in this gene are associated with spastic quadriplegic cerebral palsy-6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Dec 2011] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 12:51690966-51738939 | ||||||||
| Strand | Forward strand | ||||||||
| Band | B3 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME | |||||||||
| KEGG |
Lysosome pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME | |||||||||
| KEGG |
Lysosome pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9WVL1 | ||||||||
| TrEMBL | Q99M60 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 11782 | ||||||||
| UniGene | Mm.386749 | ||||||||
| RefSeq | NM_021710 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS36441 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1337065 | ||||||||
| MGI Symbol | Ap4s1 | ||||||||
| EMBL | AF092093 AK005283 BC001985 BC053339 | ||||||||
| GenPept | AAD20447 AAH01985 AAH53339 BAB23931 | ||||||||
| RNA Seq Atlas | 11782 | ||||||||