Mus musculus Gene: Inpp4a
Summary
InnateDB Gene IDBG-145740.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Inpp4a
Gene Name inositol polyphosphate-4-phosphatase, type I
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000026113
Encoded Proteins
inositol polyphosphate-4-phosphatase, type I
inositol polyphosphate-4-phosphatase, type I
inositol polyphosphate-4-phosphatase, type I
inositol polyphosphate-4-phosphatase, type I
inositol polyphosphate-4-phosphatase, type I
inositol polyphosphate-4-phosphatase, type I
inositol polyphosphate-4-phosphatase, type I
inositol polyphosphate-4-phosphatase, type I
inositol polyphosphate-4-phosphatase, type I
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000040933:
This gene encodes an Mg++ independent enzyme that hydrolyzes the 4-position phosphate from the inositol ring of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate, and inositol 3,4-bisphosphate. Multiple transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Aug 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:37299865-37410736
Strand Forward strand
Band B
Transcripts
ENSMUST00000027287 ENSMUSP00000027287
ENSMUST00000058307 ENSMUSP00000057233
ENSMUST00000114933 ENSMUSP00000110583
ENSMUST00000146676
ENSMUST00000136846 ENSMUSP00000121518
ENSMUST00000132401 ENSMUSP00000123071
ENSMUST00000140264 ENSMUSP00000121107
ENSMUST00000132615 ENSMUSP00000115249
ENSMUST00000137266 ENSMUSP00000121803
ENSMUST00000123124
ENSMUST00000168546 ENSMUSP00000130443
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity
GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity
Biological Process
GO:0006798 polyphosphate catabolic process
GO:0016311 dephosphorylation
GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Synthesis of IP2, IP, and Ins in the cytosol pathway
Synthesis of PIPs at the early endosome membrane pathway
Synthesis of PIPs at the plasma membrane pathway
PI Metabolism pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Phospholipid metabolism pathway
Inositol phosphate metabolism pathway
KEGG
Phosphatidylinositol signaling system pathway
Inositol phosphate metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Synthesis of PIPs at the plasma membrane pathway
Synthesis of PIPs at the early endosome membrane pathway
Synthesis of IP2, IP, and Ins in the cytosol pathway
Metabolism of lipids and lipoproteins pathway
PI Metabolism pathway
Phospholipid metabolism pathway
Inositol phosphate metabolism pathway
Metabolism pathway
KEGG
Inositol phosphate metabolism pathway
Phosphatidylinositol signaling system pathway
INOH
Inositol phosphate metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.470401 Mm.5294
RefSeq NM_001290797 NM_001290798 NM_001290799 NM_030266 NM_172971 XM_006496006 XM_006496008 XM_006496009 XM_006496012 XM_006496016 XM_006496017 XM_006496018 XM_006496019 XM_006496020
OMIM
CCDS CCDS35539 CCDS35540 CCDS69879
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas