Version 5.4
Mus musculus Gene: Olfr1446
Summary
InnateDB Gene IDBG-148588.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Olfr1446
Gene Name olfactory receptor 1446
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000057817
Encoded Proteins
IDBP-148590
olfactory receptor 1446
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:12889615-12890658
Strand Reverse strand
Band A
Transcripts
ENSMUST00000081236 ENSMUSP00000079994
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004984 olfactory receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007608 sensory perception of smell
GO:0050911 detection of chemical stimulus involved in sensory perception of smell
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
mmu04740
Olfactory transduction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q7TQR6 Q8VFX4
UniProt Splice Variant
Entrez Gene 258699
UniGene Mm.451657
RefSeq NM_146704
OMIM
CCDS CCDS29642
HPRD
IMGT
MGI ID MGI:3031280
MGI Symbol Olfr1446
EMBL AC135633 AY073391 AY318665 BC119061 BC137821 CH466534
GenPept AAI19062 AAI37822 AAL61054 AAP71816 EDL41491
RNA Seq Atlas 258699

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca