Version 5.4
Mus musculus Gene: Hsf2
Summary
InnateDB Gene IDBG-152298.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hsf2
Gene Name heat shock factor 2
Synonyms AI661205
Species Mus musculus
Ensembl Gene ENSMUSG00000019878
Encoded Proteins
IDBP-152302
heat shock factor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000025156:
The protein encoded by this gene belongs to the HSF family of transcription factors that bind specifically to the heat-shock promoter element and activate transcription. Heat shock transcription factors activate heat-shock response genes under conditions of heat or other stresses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:57486385-57513133
Strand Forward strand
Band B4
Transcripts
ENSMUST00000079833 ENSMUSP00000078761
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0042803 protein homodimerization activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006950 response to stress
GO:0007283 spermatogenesis
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000025156
View Gene Order
ENSBTAG00000012946
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
era_genomic_pathway
Validated nuclear estrogen receptor alpha network
Cross-References
SwissProt P38533
TrEMBL
UniProt Splice Variant
Entrez Gene 15500
UniGene Mm.261395 Mm.393422
RefSeq NM_008297
OMIM
CCDS CCDS23852
HPRD
IMGT
MGI ID MGI:96239
MGI Symbol Hsf2
EMBL AF045615 AF045616 AF045617 AF045618 AF045619 AF045620 AF045621 AF045622 AF045623 AF045624 AF045625 AF045626 AF045627 BC018414 S79629 X61754
GenPept AAB35307 AAD02417 AAH18414 CAA43893
RNA Seq Atlas 15500

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca