Mus musculus Gene: Arhgap4 | |||||||||||||||
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Summary | |||||||||||||||
InnateDB Gene | IDBG-154207.6 | ||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
Gene Symbol | Arhgap4 | ||||||||||||||
Gene Name | Rho GTPase activating protein 4 | ||||||||||||||
Synonyms | |||||||||||||||
Species | Mus musculus | ||||||||||||||
Ensembl Gene | ENSMUSG00000031389 | ||||||||||||||
Encoded Proteins |
Rho GTPase activating protein 4
Rho GTPase activating protein 4
Rho GTPase activating protein 4
Rho GTPase activating protein 4
Rho GTPase activating protein 4
Rho GTPase activating protein 4
Rho GTPase activating protein 4
Rho GTPase activating protein 4
Rho GTPase activating protein 4
Rho GTPase activating protein 4
Rho GTPase activating protein 4
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Protein Structure | |||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||
Entrez Gene | |||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000089820:
This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins belonging to the RAS superfamily. The protein encoded by the orthologous gene in rat is localized to the Golgi complex and can redistribute to microtubules. The rat protein stimulates the activity of some Rho GTPases in vitro. Genomic deletions of this gene and a neighboring gene have been found in patients with nephrogenic diabetes insipidus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |
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Gene Information | |||||||||||||||
Type | Protein coding | ||||||||||||||
Genomic Location | Chromosome X:73891442-73921870 | ||||||||||||||
Strand | Reverse strand | ||||||||||||||
Band | A7.3 | ||||||||||||||
Transcripts | |||||||||||||||
Interactions | |||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathway Predictions based on Human Orthology Data | |||||||||||||||
NETPATH | |||||||||||||||
REACTOME |
NRAGE signals death through JNK pathway
G alpha (12/13) signalling events pathway
Rho GTPase cycle pathway
Signalling by NGF pathway
Signaling by Rho GTPases pathway
Signaling by GPCR pathway
p75 NTR receptor-mediated signalling pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Cell death signalling via NRAGE, NRIF and NADE pathway
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KEGG | |||||||||||||||
INOH | |||||||||||||||
PID NCI |
Regulation of RhoA activity
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Cross-References | |||||||||||||||
SwissProt | |||||||||||||||
TrEMBL | |||||||||||||||
UniProt Splice Variant | |||||||||||||||
Entrez Gene | |||||||||||||||
UniGene | Mm.482337 | ||||||||||||||
RefSeq | NM_001162423 NM_001162424 NM_138630 XM_006527878 XM_006527880 XM_006527881 | ||||||||||||||
OMIM | |||||||||||||||
CCDS | CCDS41014 CCDS53100 CCDS53101 | ||||||||||||||
HPRD | |||||||||||||||
IMGT | |||||||||||||||
MGI ID | |||||||||||||||
MGI Symbol | |||||||||||||||
EMBL | |||||||||||||||
GenPept | |||||||||||||||
RNA Seq Atlas | |||||||||||||||