InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Slc39a4

Summary

InnateDB Gene

IDBG-156180.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc39a4

Gene Name

solute carrier family 39 (zinc transporter), member 4

Synonyms

1600025H15Rik; AU041686; AWMS2; ZIP4

Species

Mus musculus

Ensembl Gene

ENSMUSG00000063354

Encoded Proteins

IDBP-156182

solute carrier family 39 (zinc transporter), member 4

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147804:
This gene encodes a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The transmembrane protein is required for zinc uptake in the intestine. Mutations in this gene result in acrodermatitis enteropathica, a rare inherited defect in the absorption of dietary zinc. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 15:76612385-76616852

Strand

Reverse strand

Band

Transcripts

ENSMUST00000073428

ENSMUSP00000073134

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005385	zinc ion transmembrane transporter activity
GO:0046873	metal ion transmembrane transporter activity

Biological Process

GO:0006829	zinc ion transport
GO:0006882	cellular zinc ion homeostasis
GO:0030001	metal ion transport
GO:0034224	cellular response to zinc ion starvation
GO:0055085	transmembrane transport
GO:0071577	zinc ion transmembrane transport

Cellular Component

GO:0005768	endosome
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0016324	apical plasma membrane
GO:0055038	recycling endosome membrane
GO:0070062	extracellular vesicular exosome