Version 5.4
Mus musculus Gene: Lect2
Summary
InnateDB Gene IDBG-157368.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lect2
Gene Name leukocyte cell-derived chemotaxin 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000021539
Encoded Proteins
IDBP-157370
leukocyte cell-derived chemotaxin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000145826:
This gene encodes a secreted, 16 kDa protein that acts as a chemotactic factor to neutrophils and stimulates the growth of chondrocytes and osteoblasts. This protein has high sequence similarity to the chondromodulin repeat regions of the chicken myb-induced myeloid 1 protein. A polymorphism in this gene may be associated with rheumatoid arthritis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:56542460-56548538
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000062806 ENSMUSP00000060495
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0042802 identical protein binding
Biological Process
GO:0006935 chemotaxis
GO:0030178 negative regulation of Wnt signaling pathway
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000145826
View Gene Order
ENSBTAG00000001247
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
cmyb_pathway
C-MYB transcription factor network
Cross-References
SwissProt O88803
TrEMBL
UniProt Splice Variant
Entrez Gene 16841
UniGene Mm.16973
RefSeq NM_010702
OMIM
CCDS CCDS26564
HPRD
IMGT
MGI ID MGI:1278342
MGI Symbol Lect2
EMBL AB009687 AB009688 AB009689 AF035161 AK131971 BC027753 CH466546
GenPept AAF13302 AAH27753 BAA33383 BAA33384 BAA33385 BAA33386 BAE20911 EDL41242
RNA Seq Atlas 16841

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca