Mus musculus Gene: Gdf9
Summary
InnateDB Gene IDBG-171675.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gdf9
Gene Name growth differentiation factor 9
Synonyms Gdf-9
Species Mus musculus
Ensembl Gene ENSMUSG00000018238
Encoded Proteins
growth differentiation factor 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164404:
Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. Growth differentiation factor-9 (GDF9) is expressed in oocytes and is thought to be required for ovarian folliculogenesis. GDF9 is a member of the transforming growth factor-beta superfamily. [provided by RefSeq, Jul 2008]
This gene encodes a member of the transforming growth factor-beta superfamily. The encoded preproprotein is processed into a secreted factor that is required for ovarian folliculogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:53431023-53437904
Strand Forward strand
Band B1.3
Transcripts
ENSMUST00000018382 ENSMUSP00000018382
ENSMUST00000156037
ENSMUST00000145369
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 36 interaction(s) predicted by orthology.
Predicted by orthology
Total 36 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
GO:0008083 growth factor activity
Biological Process
GO:0001555 oocyte growth
GO:0008284 positive regulation of cell proliferation
GO:0030308 negative regulation of cell growth
GO:2000870 regulation of progesterone secretion
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
GPCR signaling pathway
BMP2 signaling pathway
TGF-beta signaling pathway
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
GPCR signaling pathway
TGF-beta signaling pathway
BMP2 signaling pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.490461 Mm.9714
RefSeq NM_008110 XM_006532220 XM_006532221
OMIM
CCDS CCDS24679
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas