Version 5.4
Mus musculus Gene: Smarcd1
Summary
InnateDB Gene IDBG-183734.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Smarcd1
Gene Name SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
Synonyms AA407987; Baf60a; D15Kz1
Species Mus musculus
Ensembl Gene ENSMUSG00000023018
Encoded Proteins
IDBP-183736
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000066117:
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:99702287-99713995
Strand Forward strand
Band F1
Transcripts
ENSMUST00000023759 ENSMUSP00000023759
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 78 interaction(s) predicted by orthology.
Experimentally validated
Total 21 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 78 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0032947 protein complex scaffold
Biological Process
GO:0006337 nucleosome disassembly
GO:0006338 chromatin remodeling
GO:0007399 nervous system development
GO:0048096 chromatin-mediated maintenance of transcription
Cellular Component
GO:0016514 SWI/SNF complex
GO:0071564 npBAF complex
GO:0071565 nBAF complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000066117
View Gene Order
ENSBTAG00000037935
Not yet available
Pathways
NETPATH
REACTOME
REACT_218274
Chromatin organization pathway
REACT_202766
Chromatin modifying enzymes pathway
REACT_244207
RMTs methylate histone arginines pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_172623
Chromatin organization pathway
REACT_228108
RMTs methylate histone arginines pathway
REACT_172633
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
reg_gr_pathway
Glucocorticoid receptor regulatory network
Cross-References
SwissProt Q61466
TrEMBL
UniProt Splice Variant
Entrez Gene 83797
UniGene Mm.273756
RefSeq NM_031842 XM_006521559
OMIM
CCDS CCDS37204
HPRD
IMGT
MGI ID MGI:1933623
MGI Symbol Smarcd1
EMBL AK075611 BC026783 BC059921 M25773 U66620
GenPept AAA53377 AAC52794 AAH26783 BAC35856
RNA Seq Atlas 83797

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca