Mus musculus Gene: Cox11 | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-208382.6 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | Cox11 | ||||||
Gene Name | COX11 homolog, cytochrome c oxidase assembly protein (yeast) | ||||||
Synonyms | 2010004I09Rik | ||||||
Species | Mus musculus | ||||||
Ensembl Gene | ENSMUSG00000020544 | ||||||
Encoded Proteins |
COX11 homolog, cytochrome c oxidase assembly protein (yeast)
COX11 homolog, cytochrome c oxidase assembly protein (yeast)
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
Entrez Gene | |||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166260:
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6. [provided by RefSeq, Jun 2009] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 11:90638173-90644931 | ||||||
Strand | Forward strand | ||||||
Band | D | ||||||
Transcripts |
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Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||
NETPATH | |||||||
REACTOME |
The citric acid (TCA) cycle and respiratory electron transport pathway
Orphan transporters pathway
Respiratory electron transport pathway
Metabolism pathway
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
Transmembrane transport of small molecules pathway
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KEGG |
Oxidative phosphorylation pathway
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INOH | |||||||
PID NCI | |||||||
Pathway Predictions based on Human Orthology Data | |||||||
NETPATH | |||||||
REACTOME |
Respiratory electron transport pathway
Transmembrane transport of small molecules pathway
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
Orphan transporters pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Metabolism pathway
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KEGG |
Oxidative phosphorylation pathway
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INOH | |||||||
PID NCI | |||||||
Cross-References | |||||||
SwissProt | Q6P8I6 | ||||||
TrEMBL | Q5SRC5 | ||||||
UniProt Splice Variant | |||||||
Entrez Gene | 69802 | ||||||
UniGene | |||||||
RefSeq | NM_199008 | ||||||
OMIM | |||||||
CCDS | CCDS25243 | ||||||
HPRD | |||||||
IMGT | |||||||
MGI ID | MGI:1917052 | ||||||
MGI Symbol | Cox11 | ||||||
EMBL | AK143937 AL646046 AL672199 BC061233 | ||||||
GenPept | AAH61233 BAE25618 CAI23913 CAI24239 | ||||||
RNA Seq Atlas | 69802 | ||||||