Version 5.4
Mus musculus Gene: Xpo6
Summary
InnateDB Gene IDBG-209411.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Xpo6
Gene Name exportin 6
Synonyms 2610005L19Rik; AI854665; AL022631; C230091E20Rik; mKIAA0370; R75304; Ranbp20
Species Mus musculus
Ensembl Gene ENSMUSG00000000131
Encoded Proteins
IDBP-209413
exportin 6
IDBP-622482
exportin 6
IDBP-622483
exportin 6
IDBP-622488
exportin 6
IDBP-622493
exportin 6
IDBP-622497
exportin 6
IDBP-622499
exportin 6
IDBP-622501
exportin 6
IDBP-622503
exportin 6
IDBP-622505
exportin 6
IDBP-622508
exportin 6
IDBP-622510
exportin 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000169180:
The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:126101715-126200501
Strand Reverse strand
Band F3
Transcripts
ENSMUST00000009344 ENSMUSP00000009344
ENSMUST00000168189 ENSMUSP00000130527
ENSMUST00000166719 ENSMUSP00000131299
ENSMUST00000167315
ENSMUST00000170675
ENSMUST00000171861 ENSMUSP00000126904
ENSMUST00000168933
ENSMUST00000168564 ENSMUSP00000129881
ENSMUST00000165608 ENSMUSP00000128919
ENSMUST00000165660 ENSMUSP00000132958
ENSMUST00000166538 ENSMUSP00000127323
ENSMUST00000167268
ENSMUST00000166540 ENSMUSP00000129658
ENSMUST00000164741 ENSMUSP00000132205
ENSMUST00000168649
ENSMUST00000169059
ENSMUST00000167147 ENSMUSP00000132462
ENSMUST00000166368
ENSMUST00000163959 ENSMUSP00000128058
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0008536 Ran GTPase binding
GO:0008565 protein transporter activity
Biological Process
GO:0006611 protein export from nucleus
GO:0006886 intracellular protein transport
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000169180
View Gene Order
ENSBTAG00000010309
Not yet available
Cross-References
SwissProt Q924Z6
TrEMBL E9Q081 E9Q6V5 F6U927 F6YJ47 F6ZUE3 F7B8F0
UniProt Splice Variant
Entrez Gene 74204
UniGene Mm.235663
RefSeq NM_028816 XM_006508247 XM_006508249
OMIM
CCDS CCDS52396
HPRD
IMGT
MGI ID MGI:2429950
MGI Symbol Xpo6
EMBL AC012297 AC135809 AK011324 AK154709 AY029528 BC058090
GenPept AAH58090 AAK40296 BAB27545 BAE32778
RNA Seq Atlas 74204

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca