Version 5.4
Mus musculus Gene: Snf8
Summary
InnateDB Gene IDBG-209793.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Snf8
Gene Name SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
Synonyms D11Moh34
Species Mus musculus
Ensembl Gene ENSMUSG00000006058
Encoded Proteins
IDBP-209795
SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
IDBP-266105
SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000159210:
SNF8, VPS25 (MIM 610907), and VPS36 (MIM 610903) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL; MIM 600284) (Slagsvold et al., 2005 [PubMed 15755741]; Kamura et al., 2001 [PubMed 11278625]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:96034885-96047430
Strand Forward strand
Band D
Transcripts
ENSMUST00000006217 ENSMUSP00000006217
ENSMUST00000107700 ENSMUSP00000103328
ENSMUST00000150946
ENSMUST00000156524
ENSMUST00000145749
ENSMUST00000156394
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0015031 protein transport
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0031902 late endosome membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000159210
View Gene Order
ENSBTAG00000018803
Not yet available
Pathways
NETPATH
REACTOME
REACT_209837
Membrane Trafficking pathway
REACT_198518
Endosomal Sorting Complex Required For Transport (ESCRT) pathway
KEGG
mmu04144
Endocytosis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_27258
Endosomal Sorting Complex Required For Transport (ESCRT) pathway
REACT_11123
Membrane Trafficking pathway
KEGG
hsa04144
Endocytosis pathway
INOH
PID NCI
Cross-References
SwissProt Q9CZ28
TrEMBL
UniProt Splice Variant
Entrez Gene 27681
UniGene Mm.372235 Mm.411494 Mm.460787
RefSeq NM_033568 XM_006533468
OMIM
CCDS CCDS25288
HPRD
IMGT
MGI ID MGI:1343161
MGI Symbol Snf8
EMBL AK013058 AL603682 BC003938
GenPept AAH03938 BAB28626 CAM18269
RNA Seq Atlas 27681

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca