Version 5.4
Homo sapiens Gene: PTPMT1
Summary
InnateDB Gene IDBG-43607.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PTPMT1
Gene Name protein tyrosine phosphatase, mitochondrial 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000110536
Encoded Proteins
IDBP-43609
protein tyrosine phosphatase, mitochondrial 1
IDBP-43611
protein tyrosine phosphatase, mitochondrial 1
IDBP-373643
protein tyrosine phosphatase, mitochondrial 1
IDBP-588557
protein tyrosine phosphatase, mitochondrial 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:47565430-47573461
Strand Forward strand
Band p11.2
Transcripts
ENST00000326656 ENSP00000325882
ENST00000326674 ENSP00000325958
ENST00000426530 ENSP00000410272
ENST00000534775 ENSP00000436160
ENST00000527079
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0008138 protein tyrosine/serine/threonine phosphatase activity
GO:0008962 phosphatidylglycerophosphatase activity
GO:0016791 phosphatase activity
Biological Process
GO:0006470 protein dephosphorylation
GO:0006644 phospholipid metabolic process
GO:0006655 phosphatidylglycerol biosynthetic process
GO:0016311 dephosphorylation
GO:0032049 cardiolipin biosynthetic process
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0044281 small molecule metabolic process
GO:0046474 glycerophospholipid biosynthetic process
GO:0046855 inositol phosphate dephosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0031305 integral component of mitochondrial inner membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000063235
View Gene Order
ENSBTAG00000018479
Not yet available
Pathways
NETPATH
REACTOME
REACT_121280
Synthesis of PG pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121401
Glycerophospholipid biosynthesis pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.656205 Hs.742231
RefSeq NM_001143984 NM_175732
HUGO
OMIM
CCDS CCDS41643 CCDS44593
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca