InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: CHRNE

Summary

InnateDB Gene

IDBG-634244.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CHRNE

Gene Name

Acetylcholine receptor subunit epsilon

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000004908

Encoded Proteins

IDBP-686007

Acetylcholine receptor subunit epsilon

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000108556:
Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome. [provided by RefSeq, Sep 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:27118517-27123114

Strand

Forward strand

Band

Transcripts

ENSBTAT00000045415

ENSBTAP00000042804

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004889	acetylcholine-activated cation-selective channel activity
GO:0005216	ion channel activity
GO:0005230	extracellular ligand-gated ion channel activity

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0006812	cation transport
GO:0034220	ion transmembrane transport
GO:0042391	regulation of membrane potential

Cellular Component

GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030054	cell junction
GO:0045202	synapse
GO:0045211	postsynaptic membrane