Version 5.4
Bos taurus Gene: ARHGEF4
Summary
InnateDB Gene IDBG-638970.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARHGEF4
Gene Name rho guanine nucleotide exchange factor 4
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015834
Encoded Proteins
IDBP-691084
Rho guanine nucleotide exchange factor (GEF) 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:1609041-1792901
Strand Forward strand
Band
Transcripts
ENSBTAT00000021041 ENSBTAP00000021041
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0019904 protein domain specific binding
GO:0030676 Rac guanyl-nucleotide exchange factor activity
Biological Process
GO:0030032 lamellipodium assembly
GO:0032321 positive regulation of Rho GTPase activity
GO:0032855 positive regulation of Rac GTPase activity
GO:0035023 regulation of Rho protein signal transduction
GO:0035556 intracellular signal transduction
GO:0043547 positive regulation of GTPase activity
GO:0046847 filopodium assembly
Cellular Component
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL F1MAZ5
UniProt Splice Variant
Entrez Gene 505852
UniGene Bt.26762
RefSeq NM_001192073
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02003814 DAAA02003815 DAAA02003816 DAAA02003817 DAAA02003818
GenPept
RNA Seq Atlas 505852

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca