Version 5.4
| Bos taurus Gene: PSME2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-645744.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | PSME2 | ||||||||
| Gene Name | Proteasome activator complex subunit 2 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000005814 | ||||||||
| Encoded Proteins |
Proteasome activator complex subunit 2
Proteasome activator complex subunit 2
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary | Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs. | ||||||||
| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 10:20838545-20841805 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
| No orthologs found for this gene | |||||||||
| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
APC truncation mutants have impaired AXIN binding pathway
Degradation of GLI1 by the proteasome pathway
Regulation of Apoptosis pathway
ER-Phagosome pathway pathway
Signaling by Wnt pathway
Signaling by WNT in cancer pathway
S Phase pathway
Hedgehog ligand biogenesis pathway
S33 mutants of beta-catenin aren't phosphorylated pathway
CDT1 association with the CDC6:ORC:origin complex pathway
Regulation of APC/C activators between G1/S and early anaphase pathway
Mitotic G1-G1/S phases pathway
Regulation of mRNA stability by proteins that bind AU-rich elements pathway
DNA Replication Pre-Initiation pathway
Metabolism of amino acids and derivatives pathway
GLI3 is processed to GLI3R by the proteasome pathway
Stabilization of p53 pathway
M Phase pathway
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins pathway
DNA Replication pathway
p53-Independent G1/S DNA damage checkpoint pathway
Assembly of the pre-replicative complex pathway
Separation of Sister Chromatids pathway
G1/S DNA Damage Checkpoints pathway
G1/S Transition pathway
TCF dependent signaling in response to WNT pathway
Class I MHC mediated antigen processing & presentation pathway
Regulation of DNA replication pathway
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway
Antigen processing: Ubiquitination & Proteasome degradation pathway
Orc1 removal from chromatin pathway
S37 mutants of beta-catenin aren't phosphorylated pathway
deletions in the AXIN genes in hepatocellular carcinoma result in elevated WNT signaling pathway
Mitotic Metaphase and Anaphase pathway
Mitotic Anaphase pathway
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 pathway
Gene Expression pathway
Downstream signaling events of B Cell Receptor (BCR) pathway
Asymmetric localization of PCP proteins pathway
phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex pathway
Regulation of activated PAK-2p34 by proteasome mediated degradation pathway
Immune System pathway
Cell Cycle, Mitotic pathway
truncations of AMER1 destabilize the destruction complex pathway
AXIN mutants destabilize the destruction complex, activating WNT signaling pathway
Ubiquitin-dependent degradation of Cyclin D pathway
XAV939 inhibits tankyrase, stabilizing AXIN pathway
AUF1 (hnRNP D0) destabilizes mRNA pathway
Synthesis of DNA pathway
Signaling by the B Cell Receptor (BCR) pathway
Degradation of GLI2 by the proteasome pathway
Cell Cycle pathway
Signal Transduction pathway
Regulation of ornithine decarboxylase (ODC) pathway
degradation of AXIN pathway
AXIN missense mutants destabilize the destruction complex pathway
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A pathway
Hedgehog 'off' state pathway
SCF-beta-TrCP mediated degradation of Emi1 pathway
Cyclin E associated events during G1/S transition pathway
misspliced GSK3beta mutants stabilize beta-catenin pathway
Autodegradation of the E3 ubiquitin ligase COP1 pathway
beta-catenin independent WNT signaling pathway
p53-Independent DNA Damage Response pathway
SCF(Skp2)-mediated degradation of p27/p21 pathway
Regulation of mitotic cell cycle pathway
Cross-presentation of soluble exogenous antigens (endosomes) pathway
PCP/CE pathway pathway
M/G1 Transition pathway
TCF7L2 mutants don't bind CTBP pathway
p53-Dependent G1 DNA Damage Response pathway
Metabolism pathway
deletions in the AMER1 gene destabilize the destruction complex pathway
CDK-mediated phosphorylation and removal of Cdc6 pathway
AMER1 mutants destabilize the destruction complex pathway
Cyclin A:Cdk2-associated events at S phase entry pathway
APC/C-mediated degradation of cell cycle proteins pathway
Processing-defective Hh variants abrogate ligand secretion pathway
Adaptive Immune System pathway
Signaling by Hedgehog pathway
RNF mutants show enhanced WNT signaling and proliferation pathway
Activation of NF-kappaB in B cells pathway
APC/C:Cdc20 mediated degradation of mitotic proteins pathway
degradation of DVL pathway
Ubiquitin-dependent degradation of Cyclin D1 pathway
S45 mutants of beta-catenin aren't phosphorylated pathway
APC truncation mutants are not K63 polyubiquitinated pathway
p53-Dependent G1/S DNA damage checkpoint pathway
Hh ligand biogenesis disease pathway
Removal of licensing factors from origins pathway
Cell Cycle Checkpoints pathway
Disease pathway
Degradation of beta-catenin by the destruction complex pathway
Antigen processing-Cross presentation pathway
Switching of origins to a post-replicative state pathway
Apoptosis pathway
T41 mutants of beta-catenin aren't phosphorylated pathway
Autodegradation of Cdh1 by Cdh1:APC/C pathway
truncated APC mutants destabilize the destruction complex pathway
APC/C:Cdc20 mediated degradation of Securin pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | |||||||||
| UniGene | Bt.48996 | ||||||||
| RefSeq | NM_001014889 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | |||||||||
| GenPept | |||||||||
| RNA Seq Atlas | |||||||||