Version 5.4
Homo sapiens Gene: MOG
Summary
InnateDB Gene IDBG-73515.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MOG
Gene Name myelin oligodendrocyte glycoprotein
Synonyms BTN6; BTNL11; MOGIG2; NRCLP7
Species Homo sapiens
Ensembl Gene ENSG00000204655
Encoded Proteins
IDBP-73517
myelin oligodendrocyte glycoprotein
IDBP-73521
myelin oligodendrocyte glycoprotein
IDBP-73527
myelin oligodendrocyte glycoprotein
IDBP-73529
myelin oligodendrocyte glycoprotein
IDBP-73531
myelin oligodendrocyte glycoprotein
IDBP-73533
myelin oligodendrocyte glycoprotein
IDBP-73535
myelin oligodendrocyte glycoprotein
IDBP-236931
myelin oligodendrocyte glycoprotein
IDBP-236933
myelin oligodendrocyte glycoprotein
IDBP-367541
myelin oligodendrocyte glycoprotein
IDBP-367549
myelin oligodendrocyte glycoprotein
IDBP-475541
myelin oligodendrocyte glycoprotein
IDBP-475017
myelin oligodendrocyte glycoprotein
IDBP-476355
myelin oligodendrocyte glycoprotein
IDBP-477224
myelin oligodendrocyte glycoprotein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:29656981-29672372
Strand Forward strand
Band p22.1
Transcripts
ENST00000376917 ENSP00000366115
ENST00000376903 ENSP00000366101
ENST00000376889 ENSP00000366086
ENST00000376898 ENSP00000366095
ENST00000376891 ENSP00000366088
ENST00000376894 ENSP00000366091
ENST00000376888 ENSP00000366085
ENST00000396704 ENSP00000379932
ENST00000396701 ENSP00000379929
ENST00000416766 ENSP00000409394
ENST00000431798 ENSP00000410866
ENST00000469353
ENST00000483013 ENSP00000418090
ENST00000490427 ENSP00000420350
ENST00000494692 ENSP00000417405
ENST00000476244
ENST00000469603
ENST00000485211 ENSP00000418872
ENST00000485885
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
GO:0007417 central nervous system development
GO:0034126 positive regulation of MyD88-dependent toll-like receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000076439
View Gene Order
ENSBTAG00000017818
Not yet available
Cross-References
SwissProt Q16653
TrEMBL
UniProt Splice Variant
Entrez Gene 4340
UniGene Hs.141308
RefSeq NM_001008228 NM_001008229 NM_001170418 NM_002433 NM_206809 NM_206810 NM_206811 NM_206812 NM_206814 XM_005249131
HUGO HGNC:7197
OMIM 159465
CCDS CCDS34369 CCDS34366 CCDS34367 CCDS34368 CCDS34370 CCDS4667 CCDS47394 CCDS47395 CCDS54977
HPRD 11831
IMGT
EMBL AK312892 AL050328 AL645936 AL662826 AL669813 AL929591 AY566847 AY566853 BX120002 BX927250 CH471081 CR388408 CR759766 CR936483 U18798 U18799 U18800 U18801 U18803 U18840 U18843 U64564 U64565 U64566 U64567 U64568 U64569 U64570 U64571 X74511 Z48051
GenPept AAB08088 AAB08089 AAB08090 AAB08091 AAB08092 AAB08093 AAB08094 AAB08095 AAB36870 AAC50361 AAC50362 AAC50876 AAC50877 AAC50878 AAC50879 AAU09338 AAU09343 BAG35739 CAA52617 CAA88109 CAB89267 CAB89268 CAB89269 CAB89270 CAB89271 CAI17395 CAI17396 CAI17397 CAI17400 CAI17636 CAI17637 CAI18020 CAI18021 CAI18022 CAI18023 CAI18024 CAI41911 CAI41914 CAI41917 CAI95560 CAI95564 CAI95565 CAI95568 CAM25818 CAQ06614 CAQ08208 CAQ08210 CAQ08212 CAQ08213 CAQ10086 CAQ10088 CAQ10090 CAQ10091 CAQ10709 CAQ10711 CAQ10713 CAQ10714 EAX03213 EAX03214 EAX03217
RNA Seq Atlas 4340

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca