Version 5.4
| Homo sapiens Protein: AQP10 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-102929.5 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | AQP10 | ||||||||
| Protein Name | aquaporin 10 | ||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Protein | ENSP00000318355 | ||||||||
| InnateDB Gene | IDBG-102927 (AQP10) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol. {ECO:0000269PubMed:11573934, ECO:0000269PubMed:12084581}. | ||||||||
| Subcellular Localization | Membrane; Multi-pass membrane protein. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Expressed exclusively in duodenum and jejunum. Highest expression in absorptive epithelial cells at the tips of villi in the jejunum. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR000425
Major intrinsic protein IPR023271 Aquaporin-like IPR023275 Aquaporin 3 IPR026252 Aquaporin 10 |
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| PFAM |
PF00230
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| PRINTS |
PR00783
PR02015 PR02022 |
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| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q96PS8 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 89872 | ||||||||
| UniGene | Hs.259048 | ||||||||
| RefSeq | NP_536354 | ||||||||
| HUGO | HGNC:16029 | ||||||||
| OMIM | 606578 | ||||||||
| CCDS | CCDS1065 | ||||||||
| HPRD | 07361 | ||||||||
| IMGT | |||||||||
| EMBL | AB066105 AF159174 AL354980 BC069607 BC074896 BC074897 | ||||||||
| GenPept | AAH69607 AAH74896 AAH74897 AAL25998 BAB91223 CAH70482 CAH70483 | ||||||||