InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Taar8a

Summary

InnateDB Protein

IDBP-138363.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Taar8a

Protein Name

trace amine-associated receptor 8A

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000062719

InnateDB Gene

IDBG-704248 (Taar8a)

Protein Structure

UniProt Annotation

Function

Orphan olfactory receptor specific for trace amines. {ECO:0000250}.

Subcellular Localization

Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Specifically expressed in neurons of the olfactory epithelium. {ECO:0000269PubMed:16878137}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001594	trace-amine receptor activity
GO:0004871	signal transducer activity
GO:0004872	receptor activity
GO:0004930	G-protein coupled receptor activity
GO:0008227	G-protein coupled amine receptor activity

Biological Process

GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway

Cellular Component

GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:2685076

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR009132 Trace amine associated receptor family
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx
IPR019430 7TM GPCR, serpentine receptor class x (Srx)

PFAM

PF00001
PF10320
PF10328

PRINTS

PR00237
PR01830

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q5QD07