Version 5.4
Mus musculus Protein: Gm13305
Summary
InnateDB Protein IDBP-138857.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gm13305
Protein Name predicted gene 13305
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000095725
InnateDB Gene IDBG-138855 (Gm13305)
Protein Structure
UniProt Annotation
Function Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells.
Subcellular Localization Membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity Expression restricted to testis, lymph node and thymus. Highest level in testis. {ECO:0000269PubMed:9073505}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004896 cytokine receptor activity
GO:0005515 protein binding
Biological Process
GO:0019221 cytokine-mediated signaling pathway
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:3801997
InterPro IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR013151 Immunoglobulin
PFAM PF00041
PF01108
PF00047
PRINTS
PIRSF
SMART SM00409
SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P70225
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 16158
UniGene Mm.458019
RefSeq NP_001094066
MGI ID
MGI Symbol Gm13305
OMIM
CCDS CCDS51150
HPRD
IMGT
EMBL AL824709 BC132549 BC138592 BC145341 U69491 X94157 X94158 X94159 X94160 X94161 X98519
GenPept AAC53114 AAI32550 AAI38593 AAI45342 CAA63872 CAA67144 CAM22847

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca