Version 5.4
Mus musculus Protein: Fpr-rs6
Summary
InnateDB Protein IDBP-141444.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fpr-rs6
Protein Name formyl peptide receptor, related sequence 6
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000093296
InnateDB Gene IDBG-141442 (Fpr-rs6)
Protein Structure
UniProt Annotation
Function May have an olfactory function associated with the identification of pathogens or of pathogenic states. {ECO:0000269PubMed:19387439}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed exclusively in vomeronasal tissue (PubMed:19387439 and PubMed:19497865). Expressed in 1.2 % of a subset of sensory neurons located in the apical layer of the vomeronasal organ. Each neuron appears to express only one receptor gene. Expressed in brain, spleen, skeletal muscle and at high level in testis (PubMed:12459252). {ECO:0000269PubMed:12459252, ECO:0000269PubMed:19387439, ECO:0000269PubMed:19497865}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004982 N-formyl peptide receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2448176
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR017452 GPCR, rhodopsin-like, 7TM
PFAM PF00001
PRINTS PR00237
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3SXG2
PhosphoSite PhosphoSite-Q3SXG2
TrEMBL
UniProt Splice Variant
Entrez Gene 321020
UniGene Mm.377882
RefSeq NP_796290
MGI ID
MGI Symbol Fpr-rs6
OMIM
CCDS CCDS28423
HPRD
IMGT
EMBL AF437512 BC104318 BC104319
GenPept AAI04319 AAI04320 AAN63620

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca