Version 5.4
Mus musculus Protein: Serpinb1c
Summary
InnateDB Protein IDBP-142550.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Serpinb1c
Protein Name serine (or cysteine) peptidase inhibitor, clade B, member 1c
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000021834
InnateDB Gene IDBG-260574 (Serpinb1c)
Protein Structure
UniProt Annotation
Function Regulates the activity of the neutrophil proteases. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in heart. {ECO:0000269PubMed:12189154}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
Biological Process
GO:0010951 negative regulation of endopeptidase activity
GO:0030162 regulation of proteolysis
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:2445363
InterPro IPR023796 Serpin domain
PFAM PF00079
PRINTS
PIRSF
SMART SM00093
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5SV42
PhosphoSite PhosphoSite-Q5SV42
TrEMBL
UniProt Splice Variant
Entrez Gene 380839
UniGene Mm.250802
RefSeq NP_766639
MGI ID
MGI Symbol Serpinb1c
OMIM
CCDS CCDS26429
HPRD
IMGT
EMBL AF521699 AL606533 AL645693 BC104332
GenPept AAI04333 AAM95935 CAI24600 CAI25076 CAI25077

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca