Version 5.4
Mus musculus Protein: Gkn1
Summary
InnateDB Protein IDBP-165665.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gkn1
Protein Name gastrokine 1
Synonyms 2200002K21Rik; AMP-18; BRICD1; Fov;
Species Mus musculus
Ensembl Protein ENSMUSP00000032129
InnateDB Gene IDBG-165663 (Gkn1)
Protein Structure
UniProt Annotation
Function Has mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium. {ECO:0000269PubMed:12851218}.
Subcellular Localization Secreted {ECO:0000269PubMed:12851218}.
Disease Associations
Tissue Specificity Highly expressed specifically in surface cells of the antrum mucosa from where it is secreted. {ECO:0000269PubMed:12851218}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008083 growth factor activity
Biological Process
GO:0008284 positive regulation of cell proliferation
GO:0051781 positive regulation of cell division
Cellular Component
GO:0005576 extracellular region
GO:0030141 secretory granule
Protein Structure and Domains
PDB ID MGI:1913533
InterPro IPR007084 BRICHOS domain
PFAM PF04089
PRINTS
PIRSF
SMART SM01039
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CR36
PhosphoSite PhosphoSite-
TrEMBL Q53YU8
UniProt Splice Variant
Entrez Gene 66283
UniGene Mm.46414
RefSeq NP_079742
MGI ID
MGI Symbol Gkn1
OMIM
CCDS CCDS20319
HPRD
IMGT
EMBL AC153853 AK008622 AK008641 AK008647 AK008722 AK008745 AK008933 AK008956 AK008990 AK009145 AK019050 AK028136 AY139183 AY456960 BC099446 BC132540 BC132542 CH466523
GenPept AAH99446 AAI32541 AAI32543 AAN75448 AAR21210 BAB25784 BAB25801 BAB25805 BAB25856 BAB25872 BAB25975 BAB26010 BAB26103 BAB31525 BAE20436 EDK99203

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca