Version 5.4
Mus musculus Protein: Gxylt2
Summary
InnateDB Protein IDBP-173088.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gxylt2
Protein Name glucoside xylosyltransferase 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000032157
InnateDB Gene IDBG-173086 (Gxylt2)
Protein Structure
UniProt Annotation
Function Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0016757 transferase activity, transferring glycosyl groups
GO:0035252 UDP-xylosyltransferase activity
Biological Process
GO:0016266 O-glycan processing
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2682940
InterPro IPR002495 Glycosyl transferase, family 8
IPR029044 Nucleotide-diphospho-sugar transferases
PFAM PF01501
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q810K9
PhosphoSite PhosphoSite-Q810K9
TrEMBL
UniProt Splice Variant
Entrez Gene 232313
UniGene Mm.272037
RefSeq NP_941014
MGI ID
MGI Symbol Gxylt2
OMIM
CCDS CCDS20390
HPRD
IMGT
EMBL BC049816
GenPept AAH49816

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca