InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Krtap26-1

Summary

InnateDB Protein

IDBP-173934.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Krtap26-1

Protein Name

keratin associated protein 26-1

Synonyms

2310002B14Rik; AI507462;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000093626

InnateDB Gene

IDBG-173932 (Krtap26-1)

Protein Structure

UniProt Annotation

Function

In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0008150

biological_process

Cellular Component

GO:0005575	cellular_component
GO:0005882	intermediate filament

Protein Structure and Domains

PDB ID

MGI:1916783

InterPro

IPR007951 Keratin-associated protein, PMG type

PFAM

PF05287

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9D7N2

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

69533

UniGene

Mm.30967

RefSeq

NP_081381

MGI ID

MGI Symbol

Krtap26-1

OMIM

CCDS

CCDS28298

HPRD

IMGT

EMBL

AK009086 BC128283 BC139410 BC139411

GenPept

AAI28284 AAI39411 AAI39412 BAB26061